{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:44:08Z","timestamp":1777877048367,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Beijing Anzhen Hospital High Level Research Funding","award":["2024AZC3005"],"award-info":[{"award-number":["2024AZC3005"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270427"],"award-info":[{"award-number":["82270427"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7222043"],"award-info":[{"award-number":["7222043"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7232038"],"award-info":[{"award-number":["7232038"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Therapeutic Advances in Musculoskeletal"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Takayasu arteritis (TA) is associated with an increased risk of developing complicated comorbidities, which can bring both psychological and physical burdens to the patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>TA is found to carry a high risk of developing depression. This research aimed to investigate the risk factors and prognosis of depression in TA patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design:<\/jats:title>\n                    <jats:p>A longitudinal observation cohort was conducted on TA patients with or without depression to explore the clinical characteristics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>In this cohort study, 90 TA patients were split into two groups with or without depression. Depression was evaluated by the Hospital Anxiety and Depression Scale (HADS) in TA patients. TA patients with depression were followed up for at least 3\u2009months. We used multivariate logistic regression analysis to find the risk factors and Kaplan\u2013Meier curve analysis to determine the prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>We concluded 90 TA patients in this research, 29 of whom were in depression. Indian Takayasu\u2019s Arteritis Activity Score (ITAS2010) \u2a7e2 (odds ratio (OR) (95% confidence interval, CI) 26.664 (2.004\u2013354.741), p\u2009=\u20090.013), interleukin-6 (IL-6) (OR (95% CI) 1.070 (1.022\u20131.121), p\u2009=\u20090.004), prednisone equivalents (OR (95% CI) 1.101 (1.030\u20131.177), p\u2009=\u20090.005), and carotidynia (OR (95% CI) 5.829 (1.142\u201329.751), p\u2009=\u20090.034) have been shown independent risk factors for depression in TA patients. We also identified the association between disease remission with the improvement of HADS-D score (Log-rank p\u2009=\u20090.005, hazard ratio (HR) 0.25) and depression (Log-rank p\u2009=\u20090.043, HR 0.28).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Aggressive treatment to achieve remission can promote improvement of depression in patients with TA. Screening for depression should also be performed in patients with elevated disease activity, IL-6, glucocorticoid use, and carotidynia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1759720x241296414","type":"journal-article","created":{"date-parts":[[2024,11,8]],"date-time":"2024-11-08T02:38:27Z","timestamp":1731033507000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Risk factors and prognosis of depression in Takayasu arteritis patients"],"prefix":"10.1177","volume":"16","author":[{"given":"Yaxin","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Immunology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anyuyang","family":"Fan","sequence":"additional","affiliation":[{"name":"Department of the National Clinical Research Center for Mental Disorders and Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital and the Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8880-0122","authenticated-orcid":false,"given":"Juan","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuemei","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiyu","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, Beijing Anzhen Hospital, Capital Medical University, Beijing, 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