{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:13:48Z","timestamp":1791807228095,"version":"4.3.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Parkinson\u2019s Disease"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Parkinson's disease (PD) is a slowly progressing neurodegenerative disorder, so it is likely that people with PD (PwPD) face increasing disability. PwPD thus experience various degrees of fear of progression (FoP), which can become dysfunctional.\n                    <jats:bold>Objective:<\/jats:bold>\n                    This study aims to examine the prevalence of and contributing factors to dysfunctional FoP in PwPD.\n                    <jats:bold>Methods:<\/jats:bold>\n                    The Fear of Progression Questionnaire\u2013Short Form (FoP-Q-SF) was administered along with further questionnaires for non-motor symptoms; PD motor symptoms as reported by the Unified Parkinson's Disease Rating Scale Part III (UPDRS III) were obtained from patient charts.\n                    <jats:bold>Results:<\/jats:bold>\n                    28% of the 105 PwPD (mean age 66 years, 56% Hoehn &amp; Yahr stage I\/II) were categorized as experiencing dysfunctional levels of FoP using the established cut-off score of \u226534. Our analyses revealed that the FoP-Q-SF underestimates the prevalence of dysfunctional FoP in older and non-working PwPD. Using a more appropriate cut-off, 33% of PwPD are classified as having dysfunctional levels of FoP. We found strong correlations of FoP with measures of anxiety, depression and quality of life. Disease duration was secondary to these factors. We found no associations between FoP and motor symptoms.\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Our findings confirm that dysfunctional FoP significantly impacts the psychological well-being of PwPD, affecting one in three PwPD and contributing to heightened anxiety, depression, and reduced quality of life. Future validation studies are needed to confirm the cut-off value proposed here and to enable a better integration of the concept of FoP into routine care for PwPD.\n                  <\/jats:p>","DOI":"10.1177\/1877718x251365243","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T17:54:59Z","timestamp":1763488499000},"page":"170-176","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Fear of progression in Parkinson's disease: Role of age and occupational status"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2133-714X","authenticated-orcid":false,"given":"Simone","family":"D\u2019Souza","sequence":"first","affiliation":[{"name":"Department of Neurology, University Hospital Carl Gustav Carus Dresden at TU Dresden, Dresden, Germany"},{"name":"Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University Frankfurt, University Hospital Frankfurt, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Tekampe","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Carl Gustav Carus Dresden at TU Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2387-526X","authenticated-orcid":false,"given":"Bj\u00f6rn","family":"Falkenburger","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Carl Gustav Carus Dresden at TU Dresden, Dresden, Germany"},{"name":"German Center for Neurodegenerative Diseases, Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen (DZNE), Standort Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0870-8105","authenticated-orcid":false,"given":"Nils","family":"Schnalke","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital Carl Gustav Carus Dresden at TU Dresden, Dresden, Germany"},{"name":"German Center for Neurodegenerative Diseases, Deutsches Zentrum f\u00fcr Neurodegenerative Erkrankungen (DZNE), Standort Dresden, Dresden, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-202107"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-40187-9_2"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.13698"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1267927"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-223314"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.13937"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2022.104749"},{"key":"e_1_3_3_9_2","first-page":"274","article-title":"Progredienzangst bei brustkrebspatientinnen - validierung der kurzform des progredienzangstfragebogens PA-F-KF\/ fear of progression in breast cancer patients \u2013 validation of the short form of the fear of progression questionnaire (FoP-Q-SF)","volume":"52","author":"Mehnert A","year":"2006","unstructured":"Mehnert A, Herschbach P, Berg P, et al. Progredienzangst bei brustkrebspatientinnen - validierung der kurzform des progredienzangstfragebogens PA-F-KF\/ fear of progression in breast cancer patients \u2013 validation of the short form of the fear of progression questionnaire (FoP-Q-SF). Z F\u00fcr Psychosom Med Psychother 2006; 52: 274\u2013288.","journal-title":"Z F\u00fcr Psychosom Med Psychother"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.21618"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/08964289.2011.605399"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000254903"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.126.3.237"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1128-0471"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.genhosppsych.2018.02.011"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1159\/000487329"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007082"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/17437199.2022.2039744"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2018.04.015"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14188"}],"container-title":["Journal of Parkinson\u2019s Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1877718X251365243","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1877718X251365243","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1877718X251365243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T18:12:10Z","timestamp":1780683130000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1877718X251365243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1177\/1877718X251365243"],"URL":"https:\/\/doi.org\/10.1177\/1877718x251365243","relation":{},"ISSN":["1877-7171","1877-718X"],"issn-type":[{"value":"1877-7171","type":"print"},{"value":"1877-718X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,18]]}}}