{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T18:34:35Z","timestamp":1787596475892,"version":"build-2736575974"},"reference-count":25,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Huntington's Disease"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In the International guidelines for nutrition in Huntington's disease (HD) PEG-tubes may be considered in persons with HD (pwHD) with severe swallowing difficulties, but there are no general recommendations for when to initiate PEG-tube placement. Little is known about factors that have led to PEG-tube placements in pwHD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To study the indications and timing of the PEG-tube placement in pwHD through medical chart review. Further aims were to investigate symptoms related to dysphagia, and documentation on informed consent to placement of the PEG-tube.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective medical chart review on adult form of HD at two centers for HD in Sweden, from five years prior to the PEG-tube placement up to the closure of the data collection (minimum of 6 months post PEG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Dysphagia-related chart notes were extracted from the medical charts of 14 pwHD. Indications for the PEG-tube placement were severe dysphagia (n\u2009=\u200911), weight loss (n\u2009=\u200910), preventive action initiated by the healthcare team (n\u2009=\u20095), own request by pwHD (n\u2009=\u20093) and recurrent aspiration pneumonia (n\u2009=\u20091). BMI was fluctuating both prior to and post PEG. Information about PEG-tube was documented 3 months to 4\u00bc years before PEG and documentation on informed consent was registered on 11 pwHD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Frequency of dysphagia-related symptoms did not increase closer to PEG-tube placement and weight trends were inconclusive. Neither could be considered sufficient as an indicator of timing of PEG-tube placement. A request by the pwHD in combination with weight loss and\/or severe dysphagia appeared to be a strong indicator for PEG-tube placement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/18796397261478175","type":"journal-article","created":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T14:54:41Z","timestamp":1787324081000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Indicators of need and timing of percutaneous endoscopic gastrostomy (PEG) in people with Huntington's disease: A medical chart review study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6716-976X","authenticated-orcid":false,"given":"Malin","family":"Sixt B\u00f6rjesson","sequence":"first","affiliation":[{"name":"Sahlgrenska University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5694-0599","authenticated-orcid":false,"given":"Mathias","family":"Hall","sequence":"additional","affiliation":[{"name":"Karolinska University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4592-8822","authenticated-orcid":false,"given":"Elisabeth","family":"Winnberg","sequence":"additional","affiliation":[{"name":"Marie Cederschi\u00f6ld University"},{"name":"Karolinska University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780199929146.001.0001"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.3233\/JHD-240044"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02493441"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-010-9302-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-020-04265-0"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.2217\/nmt.11.77"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(80)80296-X"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v26.i20.2464"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1331-8080"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.12786\/bn.2022.15.e2"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2019.1594354"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i24.7739"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.2217\/nmt.13.22"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.2217\/nmt.11.69"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000001094"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00710"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3352\/jeehp.2013.10.12"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.29.1.1"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12646"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.11.049"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-022-1743-6"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00455-021-10257-9"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.14130"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-021-02798-0"},{"key":"e_1_3_3_26_2","first-page":"126","article-title":"A methodology for conducting retrospective chart review research in child and adolescent psychiatry","volume":"15","author":"Gearing RE","year":"2006","unstructured":"Gearing RE, Mian IA, Barber J, et al. 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