{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:51:33Z","timestamp":1777877493329,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T00:00:00Z","timestamp":1716681600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Otolaryngology - Head &amp; Neck Surgery"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To assess the risk of depression in patients with chronic rhinosinusitis (CRS) in a tertiary care center and the effect of treatment on depression scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This prospective cohort study was conducted at King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, between November 2021 and June 2022 and included adult patients (\u226514\u2009years) with CRS. The validated Arabic or English Sinonasal Outcome Test (SNOT-22) and Patient Health Questionnaire-9 (PHQ-9) were used before treatment and 3 to 6\u2009months after surgery and maximal medical treatment. PHQ-9 scores were compared at baseline and follow-up visits. The relationship between changes in SNOT-22 and PHQ-9 scores were assessed using Spearman\u2019s correlation and simple linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 38 participants with a mean\u2009\u00b1\u2009SD age of 32.7\u2009\u00b1\u200912\u2009years were enrolled. CRS with nasal polyps (55.26%) was the most frequently seen condition, followed by allergic fungal CRS (31.58%) and CRS without nasal polyps (13.16%). Six patients (15.7%) had PHQ-9 scores \u226510, indicating they had major depressive disorder. PHQ-9 and SNOT-22 scores improved significantly after treatment (3.7\u2009\u00b1\u20095.8 vs 6.5\u2009\u00b1\u20096.9 pretreatment, P\u2009=\u2009.001; 20.7\u2009\u00b1\u200920.5 vs 45.6\u2009\u00b1\u200928.9 pretreatment, P\u2009&lt;\u2009.0001, respectively). Mean\u2009\u00b1\u2009SD change in PHQ-9 and SNOT-22 scores was \u22122.7\u2009\u00b1\u20097 and \u221224.9\u2009\u00b1\u200929.8, respectively. SNOT-22 and PHQ-9 scores were positively correlated ( r\u2009=\u2009.522, P\u2009&lt;\u2009.001). PHQ-9 score change was significantly associated with SNOT-22 score change (\u03b2\u2009=\u2009.178, 95% confidence interval 0.12-0.23, P\u2009&lt;\u2009.0001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CRS affects the quality of life and psychological well-being of patients. Patient-centered care with maximal medical and surgical treatment help overcome its deleterious consequences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19160216241248668","type":"journal-article","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T02:25:06Z","timestamp":1716776706000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Does Managing Patients With Chronic Rhinosinusitis Improve Their Depression Score? Prospective Study"],"prefix":"10.1177","volume":"53","author":[{"given":"Hesham Saleh","family":"Almofada","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery and Communications Sciences, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"},{"name":"College of Medicine, Al Faisal University, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasser","family":"Almutairi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery and Communications Sciences, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"},{"name":"College of Medicine, Al Faisal University, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haifa","family":"Aldakhil","sequence":"additional","affiliation":[{"name":"Biostatics, Epidemiology and Scientific Computing Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghassan","family":"Alokby","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery and Communications Sciences, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia"},{"name":"College of Medicine, Al Faisal University, Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,5,26]]},"reference":[{"key":"bibr1-19160216241248668","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2016.30.4297"},{"key":"bibr2-19160216241248668","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2016.30.4343"},{"key":"bibr3-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819886852"},{"key":"bibr4-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1177\/070674370605100206"},{"key":"bibr5-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1177\/070674370404900208"},{"key":"bibr6-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1177\/01945998221082538"},{"key":"bibr7-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1177\/000348940811700105"},{"key":"bibr8-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21776"},{"key":"bibr9-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.3810"},{"key":"bibr10-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1177\/0194599810391625"},{"key":"bibr11-19160216241248668","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin17.238"},{"key":"bibr12-19160216241248668","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.075"},{"key":"bibr13-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200202000-00020"},{"key":"bibr14-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21820"},{"key":"bibr15-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1186\/s12991-017-0155-1"},{"key":"bibr16-19160216241248668","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2018.22"},{"key":"bibr17-19160216241248668","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.4447"},{"key":"bibr18-19160216241248668","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.401"},{"key":"bibr19-19160216241248668","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino15.072"},{"key":"bibr20-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"bibr21-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.4103"},{"key":"bibr22-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22406"},{"key":"bibr23-19160216241248668","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2021.0204"}],"container-title":["Journal of Otolaryngology - Head &amp; 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