{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:44:45Z","timestamp":1790635485690,"version":"4.1.0"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Shanghai Medical innovation project, China","award":["Grants#22Y11902100"],"award-info":[{"award-number":["Grants#22Y11902100"]}]},{"name":"Technology Agency of Jinhua city, China","award":["Grants#2022-3-042"],"award-info":[{"award-number":["Grants#2022-3-042"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Otolaryngology - Head &amp; Neck Surgery"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The objective of this study was to compare the outcomes of endoscopic cartilage myringoplasty (ECM) with or without plasma radiofrequency (RF) tuboplasty (PRT) for repairing chronic large perforation with Eustachian tube dysfunction (ETD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Chronic large perforations with ETD were randomly divided into receiving ECM or ECM plus PRT. During the 24\u2009months follow-up, the Eustachian tube score (ETS), Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7), ET inflammation scale, hearing results, and graft success rate of the patients were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 61 subjects were included in the study. Difference of ETS was significant before and after surgery in the ECM\u2009+\u2009PRT group ( P\u2009&lt;\u2009.05) but the ECM group was not ( P\u2009&gt;\u2009.05). Also, significant between-group difference was found regardless of post-24\u2009months ETS and improvement value. Postoperative ETDQ-7 scores were significantly reduced compared with preoperative ETDQ-7 scores in both groups ( P\u2009&lt;\u2009.05), also, significant between-group difference was found regardless of post-24\u2009months ETDQ-7 scores and improvement value. The graft success rate was 86.7% in the ECM group and 96.8% in the ECM\u2009+\u2009PRT group at postoperative 24\u2009months ( P\u2009&gt;\u2009.05). In addition, although the ECM\u2009+\u2009PRT group showed a better air-bone gap improvement than the ECM group, the difference was not significant (13.01\u2009\u00b1\u20092.97 vs 10.92\u2009\u00b1\u20090.69\u2009dB; P\u2009&gt;\u2009.05). No PRT procedure-related serious adverse events were reported during the follow-up process. No patients developed atelectasis or otitis media with effusion in either group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ECM combined with low-temperature PRT did not affect the graft success rate but showed a better long-term improvement in ETS and ETDQ-7 than cartilage myringoplasty for the treatment of chronic perforation with ETD. In addition, although PRT showed a better hearing improvement, the difference was not significant between the 2 groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19160216241291822","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T13:30:16Z","timestamp":1729517416000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Plasma Radiofrequency Tuboplasty and Cartilage Underlay Myringoplasty for Repairing Chronic Large Perforation with Eustachian Tube Dysfunction"],"prefix":"10.1177","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1085-9033","authenticated-orcid":false,"given":"Zhengcai","family":"Lou","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Wenzhou Medical University Affiliated Yiwu Hospital, Yiwu City, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihan","family":"Lou","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Center of Sleep Medicine, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Otolaryngological Institute of Shanghai Jiao Tong University, Shanghai, China"},{"name":"Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Wenzhou Medical University Affiliated Yiwu Hospital, Yiwu City, Zhejiang Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengnong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Department of Otolaryngology\u2014Head and Neck Surgery and Center of Sleep Medicine, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Otolaryngological Institute of Shanghai Jiao Tong University, Shanghai, China"},{"name":"Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, 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