{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:52:12Z","timestamp":1777877532202,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Otolaryngology - Head &amp; Neck Surgery"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>Importance<\/jats:title>\n                    <jats:p>Reparative granuloma (RG) is a rare but severe complication of otosclerosis surgery, presenting with vertigo, tinnitus, and hearing loss. Surgical intervention may offer effective symptom relief.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the effectiveness of surgical management for RG following otosclerosis surgery in alleviating vestibular symptoms and preserving hearing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study (STROBE guidelines).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Tertiary referral center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Nineteen adult patients with histologically confirmed RG and persistent symptoms (vertigo and\/or hearing loss) within 3\u2009months of primary stapes surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>Revision surgery included granuloma resection, prosthesis replacement, and corticosteroid-soaked graft placement as needed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Outcome Measures<\/jats:title>\n                    <jats:p>Postoperative relief of vestibular symptoms, hearing thresholds [pure-tone average (PTA)], and length of hospital stay.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Symptoms developed on average 3.6\u2009\u00b1\u20093.9\u2009days postoperatively. Revision surgery resolved vertigo in 18 of 19 patients (95%) by discharge (mean 4.8\u2009\u00b1\u20091.9\u2009days). Audiometric improvement was limited, with 11 patients retaining serviceable hearing. Preoperative versus postoperative bone conduction PTA showed no significant change (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.58).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Surgical management effectively alleviates vestibular symptoms associated with RG but has minimal impact on hearing restoration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Relevance<\/jats:title>\n                    <jats:p>This study highlights the efficacy of revision surgery for RG in addressing vestibular symptoms. Further multicenter studies are warranted to better understand reparative granuloma and improve treatment strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19160216251364762","type":"journal-article","created":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T10:07:42Z","timestamp":1755770862000},"source":"Crossref","is-referenced-by-count":1,"title":["Surgical Management of Stapedo-Vestibular Reparative Granuloma Following Otosclerosis Surgery: A STROBE Retrospective Study"],"prefix":"10.1177","volume":"54","author":[{"given":"Alexandre","family":"Krief","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Fondation Adolphe de Rothschild, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"Ayache","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Fondation Adolphe de Rothschild, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria-Pia","family":"Tuset","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Fondation Adolphe de Rothschild, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexia","family":"Tran","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Fondation Adolphe de Rothschild, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu","family":"Veyrat","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Fondation Adolphe de Rothschild, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9815-1602","authenticated-orcid":false,"given":"Mary","family":"Daval","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Fondation Adolphe de Rothschild, Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5034-4210","authenticated-orcid":false,"given":"St\u00e9phane","family":"Gargula","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Hospital La Conception, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2017.11.015"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182096da1"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215117000627"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1974.00780040179003"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0385-8146(01)00106-7"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000098845"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000098844"},{"issue":"2","key":"e_1_3_3_9_2","first-page":"155","article-title":"Update of reparative granuloma: survey of the American Otological Society and the American Neurotology Society","volume":"15","author":"Seicshnaydre MA","year":"1994","unstructured":"Seicshnaydre MA, Sismanis A, Hughes GB. 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