{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:36:53Z","timestamp":1777372613612,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"1-2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Academic Forensic Pathology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>Acute intravascular hemolysis is a rare and often lethal complication of Clostridium perfringens septicemia.Clostridium perfringens is an anaerobic, gram-positive spore-forming rod which is commonly implicated in cases of food poisoning, gas gangrene, and severe hemolytic anemia in humans via the alpha-toxin (phospholipase C). We report an interesting and rare case of a 72-year-old woman who developed massive intravascular hemolysis secondary to C perfringens bacteremia in the setting of poorly differentiated high-grade endometrial malignancy.<\/jats:p>","DOI":"10.1177\/1925362119851240","type":"journal-article","created":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T07:36:10Z","timestamp":1567755370000},"page":"127-133","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Clostridium Perfringens Bacteremia with Acute Hemolytic Anemia in the Setting of Endometrial Malignancy"],"prefix":"10.1177","volume":"9","author":[{"given":"Luke R.","family":"Cypher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelina","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,9,6]]},"reference":[{"key":"bibr1-1925362119851240","doi-asserted-by":"crossref","unstructured":"Dempsey A. Serious infection associated with induced abortion in the United States. Clin Obstet Gynecol. 2012 Dec; 55(4):888\u201392. PMID: 23090457. https:\/\/doi.org\/10.1097\/GRF.0b013e31826fd8f8.","DOI":"10.1097\/GRF.0b013e31826fd8f8"},{"key":"bibr2-1925362119851240","doi-asserted-by":"crossref","unstructured":"Kaufmann BM, Cooper JM, Cookson P. Clostridium perfringens septicemia complicating degenerating uterine leiomyomas. Am J Obstet Gynecol. 1974 Mar 15; 118(6):877\u20138. PMID: 4361157. https:\/\/doi.org\/10.1016\/0002-9378(74)90506-7.","DOI":"10.1016\/0002-9378(74)90506-7"},{"key":"bibr3-1925362119851240","doi-asserted-by":"crossref","unstructured":"Bryant CS, Perry L, Shah JP et al. Life-threatening clostridial sepsis in a postmenopausal patient with degenerating uterine leiomyoma. Case Rep Med. 2010; 2010:541959. PMID: 20585368. PMCID: PMC2878686. https:\/\/doi.org\/10.1155\/2010\/541959.","DOI":"10.1155\/2010\/541959"},{"key":"bibr4-1925362119851240","doi-asserted-by":"crossref","unstructured":"Kao MJ, Roy M, Harter J, Spencer RJ. Uterine sarcoma presenting with sepsis from clostridium perfringens endometritis in a postmenopausal woman. Case Rep Obstet Gynecol. 2018 Apr 16; 2018:8217296. PMID: 29850320. PMCID: PMC5926516. https:\/\/doi.org\/10.1155\/2018\/8217296.","DOI":"10.1155\/2018\/8217296"},{"key":"bibr5-1925362119851240","doi-asserted-by":"crossref","unstructured":"Kremer KM, McDonald ME, Goodheart MJ. Uterine Clostridium perfringens infection related to gynecologic malignancy. Gynecol Oncol Rep. 2017 Sep 21; 22:55-7. PMID: 29034307. PMCID: PMC5635240. https:\/\/doi.org\/10.1016\/j.gore.2017.09.006.","DOI":"10.1016\/j.gore.2017.09.006"},{"key":"bibr6-1925362119851240","unstructured":"Ohtani S, Watanabe N, Kawata M et al. Massive intravascular hemolysis in a patient infected by a Clostridium perfringens. Acta Med Okayama. 2006 Dec; 60(6):357\u201360. PMID: 17189980. https:\/\/doi.org\/10.18926\/AMO\/30725."},{"key":"bibr7-1925362119851240","doi-asserted-by":"crossref","unstructured":"Halpin TF, Molinari JA. Diagnosis and management of clostridium perfringens sepsis and uterine gas gangrene. Obstet Gynecol Surv. 2002 Jan; 57(1):53\u20137. PMID: 11773832. https:\/\/doi.org\/10.1097\/00006254-200201000-00024.","DOI":"10.1097\/00006254-200201000-00024"},{"key":"bibr8-1925362119851240","doi-asserted-by":"crossref","unstructured":"Leal J, Gregson DB, Ross T et al. Epidemiology of clostridium species bacteremia in Calgary, Canada, 2000-2006. J Infect. 2008 Sep; 57(3):198\u2013203. PMID: 18672296. https:\/\/doi.org\/10.1016\/j.jinf.2008.06.018.","DOI":"10.1016\/j.jinf.2008.06.018"},{"key":"bibr9-1925362119851240","doi-asserted-by":"crossref","unstructured":"Cohen AL, Bhatnagar J, Reagan S et al. Toxic shock associated with Clostridium sordellii and Clostridium perfringens after medical and spontaneous abortion. Obstet Gynecol. 2007 Nov; 110(5):1027\u201333. PMID: 17978116. https:\/\/doi.org\/10.1097\/01.AOG.0000287291.19230.ba.","DOI":"10.1097\/01.AOG.0000287291.19230.ba"},{"issue":"4","key":"bibr10-1925362119851240","first-page":"235","volume":"146","author":"T\u00f6njum S","year":"1980","journal-title":"Acta Chir Scand"}],"container-title":["Academic Forensic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1925362119851240","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1925362119851240","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1925362119851240","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:53:30Z","timestamp":1777366410000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1925362119851240"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":10,"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1177\/1925362119851240"],"URL":"https:\/\/doi.org\/10.1177\/1925362119851240","relation":{},"ISSN":["1925-3621","1925-3621"],"issn-type":[{"value":"1925-3621","type":"print"},{"value":"1925-3621","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3]]}}}