{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T17:43:55Z","timestamp":1790531035662,"version":"4.1.0"},"reference-count":28,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Diabetes Sci Technol"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:p>Diabetes around the globe results in one major limb amputation every 30 seconds, over 2500 limbs lost per day. The underlying pathophysiology sometimes leads to a chronic Inflammatory stage, which may prevent appropriate healing, and therefore, the need for a clear strategy for assessing and classifying wounds and wound healing cannot be overstated. Temperature is a surrogate marker for inflammation. Quantitative thermography using a numerical index provides a useful way to assess wound healing. Advances in technology have afforded the availability of low-cost, high-resolution thermal imaging systems, which can be used to quantify sensitive changes on the skin surface and may be particularly useful to develop monitoring strategies for wounds. This article provides a standardized technique for calculating a thermal index (TI) supported with a case report from assessment of a diabetic foot ulcer. In this single case study, the TI\/wound Inflammatory index indicates a shift from negative to positive ( p &lt; .05) before it reaches zero.<\/jats:p>","DOI":"10.1177\/193229681000400402","type":"journal-article","created":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T10:35:52Z","timestamp":1389350152000},"page":"773-779","source":"Crossref","is-referenced-by-count":31,"title":["Wound Inflammatory Index: A \u201cProof of Concept\u201d Study to Assess Wound Healing Trajectory"],"prefix":"10.1177","volume":"4","author":[{"given":"Manish","family":"Bharara","sequence":"first","affiliation":[{"name":"Southern Arizona Limb Salvage Alliance (SALSA), College of Medicine, University of Arizona, Tucson, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Schoess","sequence":"additional","affiliation":[{"name":"Eden Medical, Inc., Howard Lake, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aksone","family":"Nouvong","sequence":"additional","affiliation":[{"name":"College of Podiatric Medicine, Western University of Health Sciences, Pomona, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Southern Arizona Limb Salvage Alliance (SALSA), College of Medicine, University of Arizona, Tucson, 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