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Advances in technologies like bolus advisors can assist the patients but still there a several open questions and technical challenges regarding boluses. This commentary provides an opportunity to address several of the above-mentioned factors influencing the result of bolusing. It shall draw attention to those factors and address the current opportunities, for example, continuous subcutaneous insulin infusion (CSII), as well as the need for further studies which can help to improve diabetes insulin therapy by means of the correct use of boluses.<\/jats:p>","DOI":"10.1177\/1932296816653142","type":"journal-article","created":{"date-parts":[[2016,6,6]],"date-time":"2016-06-06T21:12:59Z","timestamp":1465247579000},"page":"165-171","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Boluses in Insulin Therapy"],"prefix":"10.1177","volume":"11","author":[{"given":"Ralph","family":"Ziegler","sequence":"first","affiliation":[{"name":"Diabetes Clinic for Children and Adolescents, Muenster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guido","family":"Freckmann","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Diabetes-Technologie Forschungs- 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