{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T07:47:54Z","timestamp":1782805674536,"version":"3.54.5"},"reference-count":10,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T00:00:00Z","timestamp":1500595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:p>\n                    The objective of this article is to evaluate the study design, rational and results of Continuous Diffusion of Oxygen Therapy (CDOT) to heal diabetic foot ulcers (DFUs). The study was a double-blinded placebo controlled randomized clinical study to evaluate DFUs over a 12-week period. The primary outcome was the proportion of ulcers that healed and the secondary outcome that was reported was the time to ulcer healing. In the per protocol analysis and in the intent to treat analysis, a higher proportion of DFUs healed in the CDOT group (per protocol 46% vs 22%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .02, intent to treat 31.5% vs 15.1%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .03). CDOT patients healed ulcers faster compared to the in the sham treatment arm (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .026)\n                  <\/jats:p>","DOI":"10.1177\/1932296817717999","type":"journal-article","created":{"date-parts":[[2017,7,21]],"date-time":"2017-07-21T04:29:21Z","timestamp":1500611361000},"page":"892-893","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Does Continuous Diffusion of Oxygen Improve Diabetic Foot Ulcer Healing?"],"prefix":"10.1177","volume":"11","author":[{"given":"Lawrence A.","family":"Lavery","sequence":"first","affiliation":[{"name":"Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Easton C.","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,7,21]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.140.10.998"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.28.118"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12490"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67695-7"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-2196"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12329"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12357"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.6.1701"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.24.2.290"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e3182024864"}],"container-title":["Journal of Diabetes Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1932296817717999","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1932296817717999","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1932296817717999","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T07:31:37Z","timestamp":1782804697000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1932296817717999"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,21]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1177\/1932296817717999"],"URL":"https:\/\/doi.org\/10.1177\/1932296817717999","relation":{},"ISSN":["1932-2968","1932-2968"],"issn-type":[{"value":"1932-2968","type":"print"},{"value":"1932-2968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,21]]}}}