{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:41:11Z","timestamp":1777556471344,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T00:00:00Z","timestamp":1598659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>Sensor-augmented pumps with predictive low glucose suspend function (PLGS-SAP) help patients avoid hypoglycemia and improve quality of life: in this retrospective study, we investigated long-term effects of PLGS-SAP on metabolic outcomes, acute and chronic diabetic complications, in particular cardiovascular events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>One hundred thirty-nine adults with type 1 diabetes (T1D) treated for more than 10\u2009years with continuous subcutaneous insulin infusion (CSII) were followed for 5\u2009years; 71 (Group 1) started to use PLGS-SAP, and 68 (Group 2) maintained on their non-PLGM insulin pump. Glucose control measures (hemoglobin A1c [HbA1c], acute diabetic complications), clinical outcomes (body mass index [BMI], arterial hypertension, dyslipidemia), chronic diabetes-related complications, and device utilization (continuous glucose monitoring utilization, use of temporary basal rates or special boluses, carbohydrate counting usage) were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The reduction of HbA1c was significant in Group 1 (from 7.5%\u2009\u00b1\u20091.1% to 7.0%\u2009\u00b1\u20091.0%, P\u2009=\u2009.02), while in Group 2 it did not reach statistical significance (from 7.5%\u2009\u00b1\u20091.1% to 7.4%\u2009\u00b1\u20090.9%, P\u2009=\u2009.853). BMI increased significantly in Group 2 (from 25.3\u2009\u00b1\u20092.8 to 25.7\u2009\u00b1\u20093.4, P\u2009&lt;\u2009.001), but not in Group 1 (from 25.2\u2009\u00b1\u20093.5 to 25.2\u2009\u00b1\u20092.8, P\u2009=\u2009.887). There were no statistically significant differences in occurrence of acute diabetes complications, other clinical outcomes, prevalence of diabetes-related complications, or device utilization between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In our five-year follow-up experience with T1D CSII users, PLGS-SAP has resulted efficient in improving metabolic control and maintaining the body weight.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1932296820952107","type":"journal-article","created":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T06:27:32Z","timestamp":1598682452000},"page":"1303-1307","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Predictive Low Glucose Suspend Algorithm in Real Life: A Five-Year Follow-Up Retrospective Analysis"],"prefix":"10.1177","volume":"15","author":[{"given":"Claudio","family":"Tubili","sequence":"first","affiliation":[{"name":"Diabetes Unit, \u201cS. Camillo-Forlanini\u201d Hospital, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Pollakova","sequence":"additional","affiliation":[{"name":"Diabetes Unit, \u201cS. Camillo-Forlanini\u201d Hospital, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Rosaria","family":"Nardone","sequence":"additional","affiliation":[{"name":"Diabetes Unit, \u201cS. Camillo-Forlanini\u201d Hospital, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0531-7691","authenticated-orcid":false,"given":"Ugo","family":"Di Folco","sequence":"additional","affiliation":[{"name":"Diabetes Unit, \u201cS. Camillo-Forlanini\u201d Hospital, Rome, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,8,29]]},"reference":[{"key":"bibr1-1932296820952107","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.19.4.324"},{"key":"bibr2-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12121"},{"key":"bibr3-1932296820952107","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-157-5-201209040-00508"},{"key":"bibr4-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052187"},{"key":"bibr5-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309303291401"},{"key":"bibr6-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1177\/1932296817702170"},{"key":"bibr7-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2013.0090"},{"key":"bibr8-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-009-1365-0"},{"key":"bibr9-1932296820952107","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-2584"},{"key":"bibr10-1932296820952107","doi-asserted-by":"publisher","DOI":"10.2337\/dc18-0771"},{"key":"bibr11-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(19)30150-0"},{"key":"bibr12-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2018.0199"},{"key":"bibr13-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.11708"},{"key":"bibr14-1932296820952107","unstructured":"AMD, SID. Standard italiani per la cura del diabete mellito 2009-2010. Edizioni Infomedica."},{"key":"bibr15-1932296820952107","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.12944"},{"key":"bibr16-1932296820952107","doi-asserted-by":"publisher","DOI":"10.2337\/dci19-0028"}],"container-title":["Journal of Diabetes Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1932296820952107","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1932296820952107","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1932296820952107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:14:52Z","timestamp":1777400092000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1932296820952107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,29]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1177\/1932296820952107"],"URL":"https:\/\/doi.org\/10.1177\/1932296820952107","relation":{},"ISSN":["1932-2968","1932-2968"],"issn-type":[{"value":"1932-2968","type":"print"},{"value":"1932-2968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,29]]}}}