{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:49:30Z","timestamp":1787788170472,"version":"build-2784847793"},"reference-count":38,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100010897","name":"Newton Fund","doi-asserted-by":"publisher","award":["414703139"],"award-info":[{"award-number":["414703139"]}],"id":[{"id":"10.13039\/100010897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The purpose of this study was to investigate the association between the mechanical properties of plantar soft tissue and diabetes status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>51 (M\/F: 21\/30) participants with prediabetes onset (fasting blood sugar [FBS] level &gt; 100\u2009mg\/dL), age &gt;18\u2009years, and no lower limb amputation were recruited after ethical approval was granted from Pontificia Universidad Catolica del Peru ethical review board. Ultrasound reverberant shear wave elastography was used to assess the soft tissue stiffness at the 1st metatarsal head (MTH), 3rd MTH, and the heel at both feet.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Spearman\u2019s rank-order correlation (rho) test indicated a significant ( P &lt; .05) positive correlations between FBS level and the plantar soft tissue shear wave speed at the 1st MTH: rho = 0.402 (@400\u2009Hz), rho = 0.373 (@450\u2009Hz), rho = 0.474 (@500\u2009Hz), rho= 0.395 (@550\u2009Hz), and rho = 0.326 (@600\u2009Hz) in the left foot and rho = 0.364 (@450\u2009Hz) in the right foot. Mann-Whitney U test indicated a significantly ( P &lt; .05) higher shear wave speed in the plantar soft tissue with the following effect sizes (r) at the 1st MTH of the left foot at all tested frequencies: r = 0.297 (@450\u2009Hz), r = 0.345 (@500\u2009Hz), r = 0.322 (@550\u2009Hz), and r = 0.275 (@600\u2009Hz), and at the 1st MTH of right foot r = 0.286 (@400\u2009Hz) in diabetes as compared with the age and body mass index matched prediabetes group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>An association between fasting blood sugar level and the stiffness of the plantar soft tissue with higher values of shear wave speed in diabetes versus prediabetes group was observed. This indicated that the proposed approach can improve the assessment of the severity of diabetic foot complications with potential implications in patient stratification.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1932296820965259","type":"journal-article","created":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T08:42:25Z","timestamp":1603442545000},"page":"478-490","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":34,"title":["Diabetes Status is Associated With Plantar Soft Tissue Stiffness Measured Using Ultrasound Reverberant Shear Wave Elastography Approach"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2998-2883","authenticated-orcid":false,"given":"Roozbeh","family":"Naemi","sequence":"first","affiliation":[{"name":"Centre for Biomechanics and Rehabilitation Technologies, School of Life Sciences and Education, Staffordshire University, Staffordshire, 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