{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:56:05Z","timestamp":1790283365592,"version":"4.1.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T00:00:00Z","timestamp":1603670400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To compare insulin dose adjustments made by physicians to those made by an artificial intelligence-based decision support system, the Advisor Pro, in people with type 1 diabetes (T1D) using an insulin pump and self-monitoring blood glucose (SMBG).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This was a multinational, non-interventional study surveying 17 physicians from 11 countries. Each physician was asked to provide insulin dose adjustments for the settings of the pump including basal rate, carbohydrate-to-insulin ratios (CRs), and correction factors (CFs) for 15 data sets of pumps and SMBG of people with T1D (mean age 18.4 \u00b1 4.8 years; eight females; mean glycated hemoglobin 8.2% \u00b1 1.4% [66 \u00b1 11mmol\/mol]). The recommendations were compared among the physicians and between the physicians and the Advisor Pro. The study endpoint was the percentage of comparison points for which there was an agreement on the direction of insulin dose adjustments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The percentage (mean \u00b1 SD) of agreement among the physicians on the direction of insulin pump dose adjustments was 51.8% \u00b1 9.2%, 54.2% \u00b1 6.4%, and 49.8% \u00b1 11.6% for the basal, CR, and CF, respectively. The automated recommendations of the Advisor Pro on the direction of insulin dose adjustments were comparable )49.5% \u00b1 6.4%, 55.3% \u00b1 8.7%, and 47.6% \u00b1 14.4% for the basal rate, CR, and CF, respectively( and noninferior to those provided by physicians. The mean absolute difference in magnitude of change between physicians was 17.1% \u00b1 13.1%, 14.6% \u00b1 8.4%, and 23.9% \u00b1 18.6% for the basal, CR, and CF, respectively, and comparable to the Advisor Pro 11.7% \u00b1 9.7%, 10.1% \u00b1 4.5%, and 25.5% \u00b1 19.5%, respectively, significant for basal and CR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Considerable differences in the recommendations for changes in insulin dosing were observed among physicians. Since automated recommendations by the Advisor Pro were similar to those given by physicians, it could be considered a useful tool to manage T1D.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1932296820965561","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T03:45:07Z","timestamp":1603683907000},"page":"364-372","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":31,"title":["Adjustment of Insulin Pump Settings in Type 1 Diabetes Management: Advisor Pro Device Compared to Physicians\u2019 Recommendations"],"prefix":"10.1177","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3571-4938","authenticated-orcid":false,"given":"Revital","family":"Nimri","sequence":"first","affiliation":[{"name":"The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children\u2019s Medical Center of Israel, Petah, Tikva, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tal","family":"Oron","sequence":"additional","affiliation":[{"name":"The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children\u2019s Medical Center of Israel, Petah, Tikva, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ido","family":"Muller","sequence":"additional","affiliation":[{"name":"DreaMed Diabetes Ltd, Petah Tiqva, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Kraljevic","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Diabetes, UHC Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat Mart\u00edn","family":"Alonso","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Children\u2019s Endocrinology Unit, University Hospital of Salamanca, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paivi","family":"Keskinen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University Hospital of Tampere, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Milicic","sequence":"additional","affiliation":[{"name":"Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Faculty of Medicine University of Belgrade, Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asaf","family":"Oren","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology and Diabetes Unit, Dana-Dwek Children\u2019s Hospital, Tel Aviv Sourasky Medical Center, Israel"},{"name":"Sackler School of Medicine, Tel Aviv University, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios","family":"Christoforidis","sequence":"additional","affiliation":[{"name":"Pediatric Department, Aristotle University of Thessaloniki, Hippokratio General Hospital, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke","family":"den Brinker","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Division of Pediatric Endocrinology and Diabetology, Antwerp University Hospital and University of Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutgarda","family":"Bozzetto","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples \u201cFederico II\u201d, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Mario","family":"Bolla","sequence":"additional","affiliation":[{"name":"Diabetes Research Institute, IRCCS San Raffaele Hospital, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1564-2503","authenticated-orcid":false,"given":"Michal","family":"Krcma","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Diabetes and Endocrinology Unit, University Hospital Pilsen, Faculty of Medicine in Pilsen, Charles University, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa Anna","family":"Rabini","sequence":"additional","affiliation":[{"name":"Department of Diabetology, Hospital Mazzoni, Ascoli Piceno, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shadi","family":"Tabba","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital of the King\u2019s Daughters, Eastern Virginia Medical School, Norfolk, VA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizl","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Endocrinology, University of Pretoria, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andriani","family":"Vazeou","sequence":"additional","affiliation":[{"name":"A\u2019 Department of Pediatrics, Diabetes Center, P&A Kyriakou, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Maltoni","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University Hospital of Bologna Sant\u2019Orsola-Malpighi Polyclinic, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Giani","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, Humanitas Clinical and Research Center-IRCCS and Humanitas University, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eran","family":"Atlas","sequence":"additional","affiliation":[{"name":"DreaMed Diabetes Ltd, Petah Tiqva, 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