{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:18:38Z","timestamp":1793647118569,"version":"4.5.1"},"reference-count":28,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T00:00:00Z","timestamp":1683072000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Rosa and Asta Jensen foundation"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>The aim was to investigate rebound hypoglycemic and hyperglycemic events, and describe their relation to other glycemic metrics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Data from intermittently scanned continuous glucose monitoring were downloaded for 90 days for 159 persons with type 1 diabetes. A hypoglycemic event was defined as glucose &lt;3.9 mmol\/l for at least two 15-minute periods. Rebound hypoglycemia (Rhypo) was a hypoglycemic event preceded by glucose &gt;10.0 mmol\/l within 120 minutes and rebound hyperglycemia (Rhyper) was hypoglycemia followed by glucose &gt;10.0 mmol\/l within 120 minutes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 10\u2009977 hypoglycemic events were identified of which 3232 (29%) were Rhypo and 3653 (33%) were Rhyper, corresponding to a median frequency of 10.1, 2.5, and 3.0 events per person\/14 days. For 1267 (12%) of the cases, Rhypo and Rhyper coexisted. The mean peak glucose was 13.0 \u00b1 1.6 mmol\/l before Rhypo; 12.8 \u00b1 1.1 mmol\/l in Rhyper. The frequency of Rhyper was significantly (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001) correlated with Rhypo (Spearman\u2019s rho 0.84), glucose coefficient of variation (0.78), and time below range (0.69) but not with time above range (0.12,\n                      <jats:italic>P<\/jats:italic>\n                      = .13).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The strong correlation between Rhyper and Rhypo suggests an individual behavioral characteristic toward intensive correction of glucose excursions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19322968231168379","type":"journal-article","created":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T01:55:14Z","timestamp":1683165314000},"page":"1392-1398","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Rebound Hypoglycemia and Hyperglycemia in Type 1 Diabetes"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7452-2747","authenticated-orcid":false,"given":"Klavs W.","family":"Hansen","sequence":"first","affiliation":[{"name":"University Research Clinic for Innovative Patient Pathways, Diagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark"},{"name":"Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo M.","family":"Bibby","sequence":"additional","affiliation":[{"name":"Biostatistical Advisory Service, Faculty of Health, Aarhus University, Aarhus N, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,3]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2016.12.015"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2016.05.008"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/1932296820982584"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2016.0349"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2020.0619"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13304"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-1690"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc20-0738"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc19-1610"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/edm2.125"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1177\/1932296820975822"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.2337\/dci19-0028"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-05027-0"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12907"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31535-5"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-020-05360-9"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc17-1600"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-016-4146-6"},{"key":"e_1_3_3_20_2","article-title":"6. 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