{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:49:20Z","timestamp":1782978560470,"version":"3.54.5"},"reference-count":15,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T00:00:00Z","timestamp":1782604800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Novo Nordisk A\/S"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"abstract":"<jats:p>This study evaluated the usability of the CagriSema dual-chamber pen, a single-dose, single-use, pre-filled autoinjector for once-weekly subcutaneous administration of a fixed-dose combination of cagrilintide and semaglutide. Adults with overweight\/obesity (n = 85) or type 2 diabetes (n = 65) performed simulated injections after standardized training. Endpoints included injection completeness, task durations, and user feedback via the Injection Device Experience and Acceptability\u2013Ease of Use and Convenience Questionnaire (IDEA-ECQ; content validity supported by cognitive interviews, n = 50). All but one participant completed the injection successfully. Median training time was 3 minutes, and time to prepare and inject was 15 seconds. Participants rated the device easy\/very easy to use (100%), easy\/very easy to learn (98.7%), and an injection with the pen convenient (99.3%). Results were consistent across populations and unaffected by prior device experience.<\/jats:p>","DOI":"10.1177\/19322968261461530","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T05:57:23Z","timestamp":1782712643000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Ease of Use, Ease of Learning, and Convenience of the CagriSema Dual-Chamber Pen: Results From a Usability Study in Adults With Overweight, Obesity, or Type 2 Diabetes"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3415-3924","authenticated-orcid":false,"given":"Walter","family":"Gulisano","sequence":"first","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6895-6432","authenticated-orcid":false,"given":"Gitte","family":"Ter-Borch","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, Hiller\u00f8d, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Brown","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1975-9300","authenticated-orcid":false,"given":"Joshua Buron","family":"Feinberg","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Gonczi","sequence":"additional","affiliation":[{"name":"Research Collective LLC, Tempe, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Hildebrand","sequence":"additional","affiliation":[{"name":"Research Collective LLC, Tempe, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina","family":"Legere-DeJohn","sequence":"additional","affiliation":[{"name":"Novo Nordisk Inc., Plainsboro, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8138-7363","authenticated-orcid":false,"given":"Riia","family":"Sustarsic","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1441-0727","authenticated-orcid":false,"given":"Thomas","family":"Sparre","sequence":"additional","affiliation":[{"name":"Novo Nordisk A\/S, S\u00f8borg, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,28]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health Organization. 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