{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T14:06:04Z","timestamp":1784729164806,"version":"3.55.0"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T00:00:00Z","timestamp":1784419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Sinocare Inc.","award":["The study was funded by Sinocare Inc."],"award-info":[{"award-number":["The study was funded by Sinocare Inc."]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>A proprietary continuous glucose monitoring (CGM) system that uses third-generation sensor technology has previously been shown to exhibit stable, single-digit mean absolute relative difference (MARD) and 15-day wear life in adults with diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>This was a prospective, single-arm study of pediatric participants aged 2 to 17 years that were enrolled at 3 clinical centers. Participants wore 2 sensors, one on each side of the abdomen, and were randomized to assessment of device performance on days 1 and 2, days 7 to 9 or days 15 and 16. Device performance across a range of metrics was assessed by comparison with venous blood glucose values obtained using a laboratory reference device. Per-protocol results are reported for the sensor with the inferior MARD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The per-protocol set comprised 75 participants, of whom 16 were aged 2 to 5 years. The overall MARD was 8.89%, and MARDs at days 1 and 2, 7 to 9 and 15 and 16 were 8.65%, 8.70% and 9.30%, respectively. DTS error grid analyses showed that 100.0% of data pairs fell in clinically acceptable zones A+B. True alarm rates for hypoglycemia and hyperglycemia were high, at 98.6% and 98.8%, respectively. Mean sensor wear life was 14.4 days, and participant\/guardian assessments of sensor usability revealed high satisfaction with respect to system assembly, sensor insertion and overall comfort. No device-related or skin-related adverse events were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In a pediatric population, the novel CGM system demonstrated accurate and stable performance across its 15-day wear life and showed high usability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19322968261463536","type":"journal-article","created":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T04:36:22Z","timestamp":1784522182000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Performance, Safety and Usability of a Third-Generation Continuous Glucose Monitoring System in a Pediatric Population: Results From a Prospective, Multicenter Study"],"prefix":"10.1177","author":[{"given":"Fengyun","family":"Wang","sequence":"first","affiliation":[{"name":"Children\u2019s Hospital of Soochow University, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-6082-227X","authenticated-orcid":false,"given":"Frank","family":"Flacke","sequence":"additional","affiliation":[{"name":"Flacke Consulting GmbH, Mainz, Germany"},{"name":"Sinocare Inc., Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuxia","family":"Ding","sequence":"additional","affiliation":[{"name":"Women and Children\u2019s Hospital of Ningbo University, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxian","family":"Oyang","sequence":"additional","affiliation":[{"name":"Hunan Children\u2019s Hospital, Changsha, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8751-4407","authenticated-orcid":false,"given":"Haiying","family":"Wu","sequence":"additional","affiliation":[{"name":"Children\u2019s Hospital of Soochow University, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,19]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.134172"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc24-S007"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-021-05568-3"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.13451"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-024-03573-x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/193229681100500507"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.2337\/db24-987-P"},{"key":"e_1_3_3_9_2","unstructured":"ClinicalTrialsgov. NCT05806554. Accuracy and precision of the True Vie I3 continuous monitoring system: an open-label multi-center trial. Accessed August 29 2025. https:\/\/clinicaltrials.gov\/study\/NCT05806554."},{"key":"e_1_3_3_10_2","unstructured":"ClinicalTrialsgov. NCT05348928. A pilot study of the feasibility and accuracy of the TrueVie CGM system - A non-significant risk study. Accessed October 20 2025. https:\/\/clinicaltrials.gov\/study\/NCT05348928?cond=continuous%20glucose%20monitoring&viewType=Table&rank=4"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-025-06497-1"},{"key":"e_1_3_3_12_2","unstructured":"ClinicalTrialsgov. NCT05908448. The True Vie I3 continuous glucose monitoring system in pediatric patients with type 1 diabetes. Accessed August 29 2025. https:\/\/clinicaltrials.gov\/study\/NCT05908448"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.23.8.1143"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/19322968241275701"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/1932296820958754"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13300-023-01385-6"},{"key":"e_1_3_3_17_2","unstructured":"Dexcom. Dexcom G6 continuous glucose monitoring system user guide. LBL014003 Rev 012 MT23976. Accessed July 17 2025.https:\/\/s3-us-west-2.amazonaws.com\/dexcompdf\/G6-CGM-Users-Guide.pdf"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/19322968221091816"},{"key":"e_1_3_3_19_2","unstructured":"Medtronic. MiniMed\u2122 780G system with Guardian\u2122 4 sensor. System user guide. Accessed July 17 2025. https:\/\/www.medtronicdiabetes.com\/sites\/default\/files\/library\/download-library\/user-guides\/MiniMed-780G-system-user-guide-with-Guardian-4-sensor.pdf"}],"container-title":["Journal of Diabetes Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19322968261463536","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19322968261463536","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19322968261463536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T13:48:03Z","timestamp":1784728083000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19322968261463536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,19]]},"references-count":18,"alternative-id":["10.1177\/19322968261463536"],"URL":"https:\/\/doi.org\/10.1177\/19322968261463536","relation":{},"ISSN":["1932-2968","1932-2968"],"issn-type":[{"value":"1932-2968","type":"print"},{"value":"1932-2968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,19]]},"article-number":"19322968261463536"}}