{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T10:08:49Z","timestamp":1784196529342,"version":"3.55.0"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Diabetes Sci Technol"],"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study examined how automatic correction boluses (ABs) vary according to active insulin time (AIT) and glucose target settings, and how these parameters impact glycemic control in individuals with type 1 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospective data from 287 individuals with type 1 diabetes using the MiniMed 780G system in auto-mode for at least 80% of the time over a minimum period of 6 months were analyzed. The AB delivery was evaluated in relation to different AIT and glucose target settings. Glycemic outcomes, including time in range (TIR 70-180 mg\/dL), were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Automatic correction boluses accounted for 33.1% of bolus insulin and 18.3% of the total daily insulin dose (TDD). Active insulin time settings significantly influenced AB delivery: individuals using a 2-hour AIT showed higher percentages of ABs relative to both TDD and bolus insulin, as well as higher AB doses expressed in IU\/kg\/day. Shorter AIT settings were also associated with improved TIR. In contrast, glucose target settings ranging from 100 to 120 mg\/dL did not significantly affect AB delivery or TIR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Active insulin time is a key modifiable parameter influencing AB delivery and glycemic outcomes. Shorter AIT settings were associated with increased AB administration and improved TIR, whereas glucose target settings had no significant impact on these outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19322968261465689","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T07:58:02Z","timestamp":1783929482000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Active Insulin Time and Glycemic Targets on Automatic Correction Bolus Delivery"],"prefix":"10.1177","author":[{"given":"Giuseppe","family":"Papa","sequence":"first","affiliation":[{"name":"Unit of Metabolic and Endocrine Disease, \u201cCentro Catanese di Medicina e Chirurgia\u201d Clinic, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4599-8487","authenticated-orcid":false,"given":"Rossella","family":"Cannarella","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmelo","family":"Gusmano","sequence":"additional","affiliation":[{"name":"Unit of Metabolic and Endocrine Disease, \u201cCentro Catanese di Medicina e Chirurgia\u201d Clinic, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Concetta","family":"Finocchiaro","sequence":"additional","affiliation":[{"name":"Unit of Metabolic and Endocrine Disease, \u201cCentro Catanese di Medicina e Chirurgia\u201d Clinic, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Anzaldi","sequence":"additional","affiliation":[{"name":"Unit of Diabetology, Metabolic and Endocrine Diseases, \u201cCannizzaro\u201d Emergency Hospital, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianfranco","family":"Gruttadauria","sequence":"additional","affiliation":[{"name":"Unit of Diabetology, Caltanissetta Health District, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Patti","sequence":"additional","affiliation":[{"name":"Unit of Diabetology, Caltanissetta Health District, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donatella","family":"Lo Presti","sequence":"additional","affiliation":[{"name":"Unit of Pediatric Diabetology, Policlinico \u201cG. Rodolico \u2013 San Marco\u201d Teaching Hospital, University of Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Scir\u00e8 Calabrisotto","sequence":"additional","affiliation":[{"name":"Unit of Pediatric Diabetology, Policlinico \u201cG. Rodolico \u2013 San Marco\u201d Teaching Hospital, University of Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosita A.","family":"Condorelli","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"La Vignera","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aldo E.","family":"Calogero","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine, University of Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0446"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-022-03079-9"},{"issue":"6","key":"e_1_3_2_4_2","first-page":"229","article-title":"Retrospective observational study on real world use of the MiniMed\u2122 780G automated insulin delivery system: impact of the settings on autocorrection and omitted meal boluses","volume":"71","author":"Izquierdo FJE","year":"2024","unstructured":"Izquierdo FJE, Garc\u00eda MJA, Vaquero AAC, et al. Retrospective observational study on real world use of the MiniMed\u2122 780G automated insulin delivery system: impact of the settings on autocorrection and omitted meal boluses. Endocrinol Diabetes Nutr (Engl Ed). 2024;71(6):229-235.","journal-title":"Endocrinol Diabetes Nutr (Engl Ed)"},{"key":"e_1_3_2_5_2","unstructured":"MiniMed\u2122 780G System. https:\/\/www.medtronicdiabetes.com\/download-library\/minimed-780g-system. Accessed May 1 2026."},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/19322968261446967"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14807"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2021.0319"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15023"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2021.0203"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0433"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14714"}],"container-title":["Journal of Diabetes Science and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19322968261465689","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19322968261465689","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19322968261465689","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T09:46:43Z","timestamp":1784195203000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19322968261465689"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":11,"alternative-id":["10.1177\/19322968261465689"],"URL":"https:\/\/doi.org\/10.1177\/19322968261465689","relation":{},"ISSN":["1932-2968","1932-2968"],"issn-type":[{"value":"1932-2968","type":"print"},{"value":"1932-2968","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,13]]},"article-number":"19322968261465689"}}