{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T03:49:25Z","timestamp":1790826565428,"version":"4.1.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1177\/1933719109349780","type":"journal-article","created":{"date-parts":[[2009,10,15]],"date-time":"2009-10-15T00:13:35Z","timestamp":1255565615000},"page":"177-185","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Maternal Obesity and its Relationship With Spontaneous and Oxytocin-Induced Contractility of Human Myometrium In Vitro"],"prefix":"10.1007","volume":"17","author":[{"given":"Claire A.","family":"Higgins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurie","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M.","family":"Blanks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane E.","family":"Norman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"McConnachie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,12,30]]},"reference":[{"key":"17020177_CR1","first-page":"168","volume-title":"The Scottish Health Survey 2003 \u2014 Volume 2","author":"V Hirani","year":"2005","unstructured":"Hirani V. Anthropometric measures, overweight, and obesity. In: Bromley C, Sproston K, Shelton N, eds. The Scottish Health Survey 2003 \u2014 Volume 2. Edinburgh: Scottish Executive; 2005: 168\u2013206, chap 5."},{"key":"17020177_CR2","first-page":"143","volume-title":"Health Survey for England 2003. Volume 2: Risk Factors for Cardiovascular Disease","author":"V Hirani","year":"2004","unstructured":"Hirani V. Anthropometric measures, overweight, and obesity. In: Sprotston K, Primatesta P, eds. Health Survey for England 2003. Volume 2: Risk Factors for Cardiovascular Disease. London: Department of Health; 2004:143\u2013180, chap 6."},{"issue":"10","key":"17020177_CR3","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1111\/j.1471-0528.2005.00685.x","volume":"112","author":"M Kanagalingam","year":"2005","unstructured":"Kanagalingam MG, Forouhi NG, Greer IA, Sattar N. Changes in booking body mass index over a decade: retrospective analysis from a Glasgow Maternity Hospital. BJOG. 2005;112(10):1431\u20131433.","journal-title":"BJOG"},{"issue":"3","key":"17020177_CR4","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1056\/NEJM199801153380302","volume":"338","author":"S Cnattingius","year":"1998","unstructured":"Cnattingius S, Bergstrom R, Lipworth L, Kramer MS. Prepregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med. 1998;338(3):147\u2013152.","journal-title":"N Engl J Med"},{"issue":"2","key":"17020177_CR5","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1097\/01.AOG.0000107291.46159.00","volume":"103","author":"M Cedergren","year":"2004","unstructured":"Cedergren MI. Maternal morbid obesity and the risk of adverse pregnancy outcome. Obstet Gynecol. 2004;103(2): 219\u2013224.","journal-title":"Obstet Gynecol"},{"issue":"8","key":"17020177_CR6","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1038\/sj.ijo.0801670","volume":"25","author":"N Sebire","year":"2001","unstructured":"Sebire NJ, Jolly M, Harris JP, et al. Maternal obesity and pregnancy outcome: a study of 287 213 pregnancies in London. Int J Obes Relat Metab Disord. 2001;25(8):1175\u20131182.","journal-title":"Int J Obes Relat Metab Disord"},{"issue":"5","key":"17020177_CR7","doi-asserted-by":"publisher","first-page":"943","DOI":"10.1097\/01.AOG.0000142713.53197.91","volume":"104","author":"A Vahratian","year":"2004","unstructured":"Vahratian A, Zhang J, Troendle JF, Savitz DA, Siega-Riz AM. Maternal prepregnancy overweight and obesity and the pattern of labor progression in term nulliparous women. Obstet Gynecol. 2004;104(5):943\u2013951.","journal-title":"Obstet Gynecol"},{"issue":"4","key":"17020177_CR8","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.jmwh.2005.11.008","volume":"51","author":"B Graves","year":"2006","unstructured":"Graves BW, DeJoy SA, Heath A, Pekow P. Maternal body mass index, delivery route, and induction of labor in a midwifery caseload. J Midwifery Womens Health. 2006;51(4):254.","journal-title":"J Midwifery Womens Health"},{"issue":"6","key":"17020177_CR9","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1111\/j.1471-0528.2004.00546.x","volume":"112","author":"T Usha Kiran","year":"2005","unstructured":"Usha Kiran TS, Hemmadi S, Bethel J, Evans J. Outcome of pregnancy in a woman with an increased body mass index. BJOG. 2005;112(6):768\u2013772.","journal-title":"BJOG"},{"issue":"3","key":"17020177_CR10","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1111\/j.1471-0528.2006.01233.x","volume":"114","author":"J Zhang","year":"2007","unstructured":"Zhang J, Bricker L, Wray S, Quenby S. Poor uterine contractility in obese women. BJOG. 2007;114(3):343\u2013348.","journal-title":"BJOG"},{"issue":"10","key":"17020177_CR11","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1111\/j.1471-0528.2006.01038.x","volume":"113","author":"G Barau","year":"2006","unstructured":"Barau G, Robillard PY, Hulsey TC, et al. Linear association between maternal pre-pregnancy body mass index and risk of caesarean section in term deliveries. BJOG. 2006;113(10): 1173\u20131177.","journal-title":"BJOG"},{"issue":"pt 1","key":"17020177_CR12","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1113\/jphysiol.2005.098475","volume":"570","author":"K Noble","year":"2006","unstructured":"Noble K, Zhang J, Wray S. Lipid rafts, the sarcoplasmic reticulum and uterine calcium signalling: an integrated approach. J Physiol. 2006;570(pt 1):29\u201335.","journal-title":"J Physiol"},{"issue":"5","key":"17020177_CR13","doi-asserted-by":"publisher","first-page":"C982","DOI":"10.1152\/ajpcell.00120.2004","volume":"288","author":"R Smith","year":"2005","unstructured":"Smith RD, Babiychuk EB, Noble K, Draeger A, Wray S. Increased cholesterol decreases uterine activity: functional effects of cholesterol alteration in pregnant rat myometrium. Am J Physiol Cell Physiol. 2005;288(5):C982\u2013C988.","journal-title":"Am J Physiol Cell Physiol"},{"issue":"9","key":"17020177_CR14","doi-asserted-by":"publisher","first-page":"4231","DOI":"10.1210\/jc.2002-020311","volume":"87","author":"J Ramsay","year":"2002","unstructured":"Ramsay JE, Ferrell WR, Crawford L, Wallace AM, Greer IA, Sattar N. Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. J Clin Endocrinol Metab. 2002;87(9):4231\u20134237.","journal-title":"J Clin Endocrinol Metab"},{"issue":"5","key":"17020177_CR15","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1177\/1933719107306229","volume":"14","author":"J Zhang","year":"2007","unstructured":"Zhang J, Kendrick A, Quenby S, Wray S. Contractility and calcium signalling of human myometrium are profoundly affected by cholesterol manipulation: implications for labor? Reproduct Sci. 2007;14(5):456\u2013466.","journal-title":"Reproduct Sci"},{"issue":"2","key":"17020177_CR16","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.ajog.2006.01.106","volume":"195","author":"A Moynihan","year":"2006","unstructured":"Moynihan AT, Hehir MP, Glavey SV, Smith TJ, Morrison JJ. Inhibitory effect of leptin on human uterine contractility in vitro. Am J Obstet Gynecol. 2006;195(2):504.","journal-title":"Am J Obstet Gynecol"},{"issue":"2","key":"17020177_CR17","doi-asserted-by":"publisher","first-page":"E345","DOI":"10.1152\/ajpendo.1999.276.2.E345","volume":"276","author":"K McKillen","year":"1999","unstructured":"McKillen K, Thornton S, Taylor CW. Oxytocin increases the [Ca2+]i sensitivity of human myometrium during the falling phase of phasic contractions. Am J Physiol Endocrinol Metab. 1999;276(2):E345\u2013E351.","journal-title":"Am J Physiol Endocrinol Metab"},{"issue":"1","key":"17020177_CR18","doi-asserted-by":"publisher","first-page":"E77","DOI":"10.1152\/ajpendo.1994.267.1.E77","volume":"267","author":"S Szal","year":"1994","unstructured":"Szal SE, Repke JT, Seely EW, Graves SW, Parker CA, Morgan KG. [Ca2+]i signaling in pregnant human myometrium. Am J Physiol Endocrinol Metab. 1994;267(1):E77\u2013E87.","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"17020177_CR19","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-0318-1","volume-title":"Mixed-Effects Models in S and S-PLUS","author":"J Pinheiro","year":"2000","unstructured":"Pinheiro JC, Bates DM. Mixed-Effects Models in S and S-PLUS. 1st ed. New York: Springer; 2000.","edition":"1st"},{"key":"17020177_CR20","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4899-4541-9","volume-title":"An Introduction to the Bootstrap","author":"B Efron","year":"1993","unstructured":"Efron BT, Robert J. An Introduction to the Bootstrap. 1st ed. London: Chapman & Hall; 1993.","edition":"1st"},{"issue":"6","key":"17020177_CR21","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1067\/mob.2000.106249","volume":"182","author":"D Main","year":"2000","unstructured":"Main DM, Main EK, Moore DH 2nd. The relationship between maternal age and uterine dysfunction: a continuous effect throughout reproductive life [see comment]. Am J Obstet Gynecol. 2000;182(6):1312\u20131320.","journal-title":"Am J Obstet Gynecol"},{"issue":"10","key":"17020177_CR22","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.1111\/j.1471-0528.1998.tb09937.x","volume":"105","author":"A Rosenthal","year":"1998","unstructured":"Rosenthal AN, Paterson-Brown S. Is there an incremental rise in the risk of obstetric intervention with increasing maternal age? BJOG. 1998;105(10):1064\u20131069.","journal-title":"BJOG"},{"issue":"9","key":"17020177_CR23","doi-asserted-by":"publisher","first-page":"4231","DOI":"10.1210\/jc.2002-020311","volume":"87","author":"J Ramsay","year":"2002","unstructured":"Ramsay JE, Ferrell WR, Crawford L, Wallace AM, Greer IA, Sattar N. Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways. J Clin Endocrinol Metab. 2002;87(9):4231\u20134237.","journal-title":"J Clin Endocrinol Metab"},{"issue":"10","key":"17020177_CR24","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1111\/j.1471-0528.2000.tb11626.x","volume":"107","author":"M Luckas","year":"2000","unstructured":"Luckas MJ, Wray S. A comparison of the contractile properties of human myometrium obtained from the upper and lower uterine segments. BJOG. 2000;107(10):1309\u20131311.","journal-title":"BJOG"}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1177\/1933719109349780.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1177\/1933719109349780\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1933719109349780","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1177\/1933719109349780.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T01:13:07Z","timestamp":1656810787000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1177\/1933719109349780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["17020177"],"URL":"https:\/\/doi.org\/10.1177\/1933719109349780","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"value":"1933-7191","type":"print"},{"value":"1933-7205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"30 December 2010","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}