{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:35:37Z","timestamp":1792787737864,"version":"4.5.0"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Natural Science Foundation","award":["No. 81370761"],"award-info":[{"award-number":["No. 81370761"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Reprod. Sci."],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1177\/1933719117725822","type":"journal-article","created":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T04:04:08Z","timestamp":1503374648000},"page":"733-739","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Spermatozoa Expression of piR-31704, piR-39888, and piR-40349 and Their Correlation to Sperm Concentration and Fertilization Rate After ICSI"],"prefix":"10.1007","volume":"25","author":[{"given":"Long","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biwei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunquan","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinghui","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,5,1]]},"reference":[{"issue":"7","key":"2505733_CR1","doi-asserted-by":"publisher","first-page":"4104","DOI":"10.1093\/nar\/gkt132","volume":"41","author":"E Sendler","year":"2013","unstructured":"Sendler E, Johnson GD, Mao S, et al. Stability, delivery and functions of human sperm RNAs at fertilization. Nucleic Acids Res. 2013;41(7):4104\u20134117.","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"2505733_CR2","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.gene.2015.12.020","volume":"578","author":"LF Luo","year":"2016","unstructured":"Luo LF, Hou CC, Yang WX. Small non-coding RNAs and their associated proteins in spermatogenesis. Gene. 2016;578(2): 141\u2013157.","journal-title":"Gene"},{"issue":"6","key":"2505733_CR3","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1261\/rna.046482.114","volume":"21","author":"L Pantano","year":"2015","unstructured":"Pantano L, Jodar M, Bak M, et al. The small RNA content of human sperm reveals pseudogene-derived piRNAs complementary to protein-coding genes. RNA. 2015;21(6):1085\u20131095.","journal-title":"RNA"},{"issue":"2","key":"2505733_CR4","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/cr.2015.4","volume":"25","author":"P Zhang","year":"2015","unstructured":"Zhang P, Kang JY, Gou LT, et al. MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes. Cell Res. 2015; 25(2): 193\u2013207.","journal-title":"Cell Res"},{"issue":"6","key":"2505733_CR5","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1093\/humupd\/dmt031","volume":"19","author":"M Jodar","year":"2013","unstructured":"Jodar M, Selvaraju S, Sendler E, Diamond MP, Krawetz SA. The presence, role and clinical use of spermatozoal RNAs. Hum Reprod Update. 2013;19(6):604\u2013624.","journal-title":"Hum Reprod Update"},{"issue":"6004","key":"2505733_CR6","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1126\/science.1190614","volume":"330","author":"S Feng","year":"2010","unstructured":"Feng S, Jacobsen SE, Reik W. Epigenetic reprogramming in plant and animal development. Science. 2010;330(6004):622\u2013627.","journal-title":"Science"},{"key":"2505733_CR7","doi-asserted-by":"publisher","first-page":"24229","DOI":"10.1038\/srep24229","volume":"6","author":"Y Hong","year":"2016","unstructured":"Hong Y, Wang C, Fu Z, et al. Systematic characterization of seminal plasma piRNAs as molecular biomarkers for male infertility. Sci Rep. 2016;6:24229.","journal-title":"Sci Rep"},{"issue":"6","key":"2505733_CR8","doi-asserted-by":"publisher","first-page":"e1501482","DOI":"10.1126\/sciadv.1501482","volume":"2","author":"Q Yang","year":"2016","unstructured":"Yang Q, Lin J, Liu M, et al. Highly sensitive sequencing reveals dynamic modifications and activities of small RNAs in mouse oocytes and early embryos. Sci Adv. 2016;2(6):e1501482.","journal-title":"Sci Adv"},{"issue":"4","key":"2505733_CR9","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1242\/dev.131755","volume":"143","author":"S Yuan","year":"2016","unstructured":"Yuan S, Schuster A, Tang C, et al. Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development. Development. 2016;143(4):635\u2013647.","journal-title":"Development"},{"issue":"12","key":"2505733_CR10","doi-asserted-by":"publisher","first-page":"3401","DOI":"10.1093\/humrep\/der329","volume":"26","author":"SA Krawetz","year":"2011","unstructured":"Krawetz SA, Kruger A, Lalancette C, et al. A survey of small RNAs in human sperm. Hum Reprod. 2011;26(12):3401\u20133412.","journal-title":"Hum Reprod"},{"issue":"7","key":"2505733_CR11","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1016\/j.celrep.2015.07.030","volume":"12","author":"B Barckmann","year":"2015","unstructured":"Barckmann B, Pierson S, Dufourt J, et al. Aubergine iCLIP reveals piRNA-dependent decay of mRNAs involved in germ cell development in the early embryo. Cell Rep. 2015;12(7): 1205\u20131216.","journal-title":"Cell Rep"},{"issue":"6","key":"2505733_CR12","doi-asserted-by":"publisher","first-page":"e66809","DOI":"10.1371\/journal.pone.0066809","volume":"8","author":"Q Yang","year":"2013","unstructured":"Yang Q, Hua J, Wang L, et al. MicroRNA and piRNA profiles in normal human testis detected by next generation sequencing. PLoS One. 2013;8(6):e66809.","journal-title":"PLoS One"},{"issue":"1","key":"2505733_CR13","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.rbmo.2011.08.012","volume":"24","author":"Y Ye","year":"2012","unstructured":"Ye Y, Qian Y, Xu C, Jin F. Meiotic segregation analysis of embryos from reciprocal translocation carriers in PGD cycles. Reprod Biomed Online. 2012;24(1):83\u201390.","journal-title":"Reprod Biomed Online"},{"key":"2505733_CR14","volume-title":"Laboratory Manual for the Examination and Processing of Human Semen","author":"WH W Organization","year":"2010","unstructured":"Organization WH. WHO Laboratory Manual for the Examination and Processing of Human Semen. 5th ed. Geneva, Switzerland: World Health Organization; 2010.","edition":"5th ed"},{"issue":"2","key":"2505733_CR15","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.fertnstert.2015.05.003","volume":"104","author":"L Cui","year":"2015","unstructured":"Cui L, Fang L, Shi B, Qiu S Ye Y. Spermatozoa micro ribonucleic acid-34c level is correlated with intracytoplasmic sperm injection outcomes. Fertil Steril. 2015;104(2):312\u2013317. el.","journal-title":"Fertil Steril"},{"issue":"6","key":"2505733_CR16","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1038\/nprot.2008.73","volume":"3","author":"TD Schmittgen","year":"2008","unstructured":"Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc. 2008;3(6):1101\u20131108.","journal-title":"Nat Protoc"},{"issue":"4","key":"2505733_CR17","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1038\/nrm3089","volume":"12","author":"MC Siomi","year":"2011","unstructured":"Siomi MC, Sato K, Pezic D, Aravin AA. PlWI-interacting small RNAs: the vanguard of genome defence. Nat Rev Mol Cell Biol. 2011;12(4):246\u2013258.","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"5","key":"2505733_CR18","volume":"10","year":"2015","unstructured":"Gebert D, Ketting RF, Zischler H, Rosenkranz D. piRNAs from pig testis provide evidence for a conserved role of the piwi path-way in post-transcriptional gene regulation in mammals. PLoS One. 2015;10(5):e0124860.","journal-title":"PLoS One"},{"issue":"10","key":"2505733_CR19","doi-asserted-by":"publisher","first-page":"6507","DOI":"10.1074\/jbc.M809104200","volume":"284","author":"Y Unhavaithaya","year":"2009","unstructured":"Unhavaithaya Y, Hao Y, Beyret E, et al. MILI, a PlWI-interacting RNA-binding protein, is required for germ line stem cell self-renewal and appears to positively regulate translation. J Biol Chem. 2009;284(10):6507\u20136519.","journal-title":"J Biol Chem"},{"issue":"5","key":"2505733_CR20","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1261\/rna.048215.114","volume":"21","author":"J Garcia-Lopez","year":"2015","unstructured":"Garcia-Lopez J, Alonso L, Cardenas DB, et al. Diversity and functional convergence of small noncoding RNAs in male germ cell differentiation and fertilization. RNA. 2015;21(5):946\u2013962.","journal-title":"RNA"},{"issue":"1","key":"2505733_CR21","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s12864-016-3394-7","volume":"18","author":"E Capra","year":"2017","unstructured":"Capra E, Turri F, Lazzari B, et al. Small RNA sequencing of cryopreserved semen from single bull revealed altered miRNAs and piRNAs expression between high- and low-motile sperm populations. BMC Genomic. 2017;18(1):14.","journal-title":"BMC Genomic"},{"issue":"2","key":"2505733_CR22","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1111\/andr.12323","volume":"5","author":"P Plouvier","year":"2017","unstructured":"Plouvier P, Barbotin AL, Boitrelle F, et al. Extreme spermatogenesis failure: andrological phenotype and intracytoplasmic sperm injection outcomes. Andrology. 2017;5(2):219\u2013225.","journal-title":"Andrology"},{"issue":"2","key":"2505733_CR23","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1017\/S0967199417000028","volume":"25","author":"J Gandhi","year":"2017","unstructured":"Gandhi J, Hernandez RJ, Chen A, et al. Impaired hypothalamic-pituitary-testicular axis activity, spermatogenesis, and sperm function promote infertility in males with lead poisoning. Zygote. 2017;25(2):103\u2013110.","journal-title":"Zygote"},{"issue":"6","key":"2505733_CR24","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1111\/j.1365-2605.2008.00911.x","volume":"32","author":"E Moretti","year":"2009","unstructured":"Moretti E, Cosci I, Spreafico A, Serchi T, Cuppone AM, Collodel G. Semen characteristics and inflammatory mediators in infertile men with different clinical diagnoses. Int J Androl. 2009;32(6): 637\u2013646.","journal-title":"Int J Androl"},{"key":"2505733_CR25","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.eururo.2016.04.010","volume":"70","author":"R Sharma","year":"2016","unstructured":"Sharma R, Harlev A, Agarwal A, Esteves SC. Cigarette smoking and semen quality: a new meta-analysis examining the effect of the 2010 world health organization laboratory methods for the examination of human semen. Eur Urol. 2016;70: 635\u2013645.","journal-title":"Eur Urol"},{"issue":"2","key":"2505733_CR26","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1093\/humrep\/den399","volume":"24","author":"Y Li","year":"2009","unstructured":"Li Y, Lin H, Ma M, et al. Semen quality of 1346 healthy men, results from the Chongqing area of southwest China. Hum Reprod. 2009;24(2):459\u2013469.","journal-title":"Hum Reprod"},{"issue":"1","key":"2505733_CR27","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.fertnstert.2014.03.040","volume":"102","author":"A Salas-Huetos","year":"2014","unstructured":"Salas-Huetos A, Blanco J, Vidal F, Mercader JM, Garrido N, Anton E. New insights into the expression profile and function of micro-ribonucleic acid in human spermatozoa. Fertil Steril. 2014;102(1):213\u2013222 e4.","journal-title":"Fertil Steril"},{"issue":"6","key":"2505733_CR28","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1007\/s10815-017-0902-x","volume":"34","author":"T Freour","year":"2017","unstructured":"Freour T, Barragan M, Ferrer-Vaquer A, Rodriguez A, Vassena R. WBP2NL\/PAWP mRNA and protein expression in sperm cells are not related to semen parameters, fertilization rate, or reproductive outcome. J Assist Reprod Genet. 2017;34(6): 803\u2013810.","journal-title":"J Assist Reprod Genet"},{"issue":"4","key":"2505733_CR29","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1261\/rna.058859.116","volume":"23","author":"JA Toombs","year":"2017","unstructured":"Toombs JA, Sytnikova YA, Chirn GW, Ang I, Lau NC, Blower MD. Xenopus Piwi proteins interact with a broad proportion of the oocyte transcriptome. RNA. 2017;23(4):504\u2013520.","journal-title":"RNA"},{"issue":"5","key":"2505733_CR30","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1016\/j.rbmo.2014.01.008","volume":"28","author":"F Vanden Meerschaut","year":"2014","unstructured":"Vanden Meerschaut F, Nikiforaki D, Heindryckx B, De Sutter P. Assisted oocyte activation following ICSI fertilization failure. Reprod Biomed Online. 2014;28(5):560\u2013571.","journal-title":"Reprod Biomed Online"},{"issue":"5","key":"2505733_CR31","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1093\/humupd\/dmn025","volume":"14","author":"JE Swain","year":"2008","unstructured":"Swain JE, Pool TB. ART failure: oocyte contributions to unsuccessful fertilization. Hum Reprod Update. 2008; 14(5): 431\u2013446.","journal-title":"Hum Reprod Update"},{"issue":"2","key":"2505733_CR32","first-page":"645","volume":"52","author":"MR Sadeghi","year":"2011","unstructured":"Sadeghi MR, Lakpour N, Heidari-Vala H, et al. Relationship between sperm chromatin status and ICSI outcome in men with obstructive azoospermia and unexplained infertile normozoosper-mia. Rom JMorphol Embryol. 2011;52(2):645\u2013651.","journal-title":"Rom JMorphol Embryol"},{"issue":"6","key":"2505733_CR33","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/j.rbmo.2013.02.011","volume":"26","author":"L Lazaros","year":"2013","unstructured":"Lazaros L, Vartholomatos G, Pamporaki C, et al. Sperm flow cytometric parameters are associated with ICSI outcome. Reprod Biomed Online. 2013;26(6):611\u2013618.","journal-title":"Reprod Biomed Online"}],"container-title":["Reproductive Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1177\/1933719117725822.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1933719117725822","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1177\/1933719117725822\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1933719117725822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1177\/1933719117725822.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T22:06:02Z","timestamp":1656799562000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1177\/1933719117725822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["2505733"],"URL":"https:\/\/doi.org\/10.1177\/1933719117725822","relation":{},"ISSN":["1933-7191","1933-7205"],"issn-type":[{"value":"1933-7191","type":"print"},{"value":"1933-7205","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"1 May 2018","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}