{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:36:05Z","timestamp":1777876565297,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T00:00:00Z","timestamp":1730246400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 CA77598"],"award-info":[{"award-number":["P30 CA77598"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UL1TR002494"],"award-info":[{"award-number":["UL1TR002494"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:p>\n                    <jats:bold>Background and Objectives:<\/jats:bold>\n                    To evaluate weight-indexed umbilical systolic diastolic ratio (UASDR) to discriminate risk for adverse outcomes among growth restricted fetuses (FGR).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Design and Setting:<\/jats:bold>\n                    Retrospective study using prenatal ultrasound data and neonatal outcome data. Two primary outcomes: admission to intensive care and a composite outcome of severe neonatal morbidity. We included births among individuals with a singleton pregnancy at 24\u201340\u00a0weeks gestation without other indications for preterm delivery. We calculated the percentile of the measured standard UASDR, and the same value indexed to the EFW (iUASDR).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    296 pregnancies met inclusion criteria. Forty-seven percent required NICU admission and 31% developed a component of the composite outcome. The sensitivity of the iUASDR increased at lower birthweight percentiles. The positive predictive value of the standard UASDR was higher among fetuses with EFW &lt;5th % and &lt;10th % for NICU admission and composite outcome ((EFW &lt;5th %) 0.82 (95% CI: 0.71, 0.91) and 0.60 (95% CI: 0.48, 0.72) and ((EFW &lt;10th %) 0.81 (95% CI: 0.70, 0.89) and 0.58 (95% CI: 0.45, 0.69) compared with indexed values.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Discussion:<\/jats:bold>\n                    Data does not support use of the iUASDR to improve the test characteristics of the UASDR. Despite a moderate increase in specificity, the positive predictive value was low. UASDR non-indexed or standard values in conjunction with clinical findings and severity of FGR perform best.\n                  <\/jats:p>","DOI":"10.1177\/19345798241292448","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T05:57:52Z","timestamp":1733205472000},"page":"36-45","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Use of a weight indexed umbilical artery systolic diastolic ratio to predict the risk for adverse outcomes among growth restricted fetuses"],"prefix":"10.1177","volume":"18","author":[{"given":"Ruby","family":"Russell","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Gynecology and Women\u2019s Health, University of Minnesota, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5513-583X","authenticated-orcid":false,"given":"Katelyn","family":"Tessier","sequence":"additional","affiliation":[{"name":"Masonic Cancer Center, Biostatistics Core, University of Minnesota, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1745-8144","authenticated-orcid":false,"given":"Stephen","family":"Contag","sequence":"additional","affiliation":[{"name":"Division of Maternal and Fetal Medicine, Department of Obstetrics, Gynecology and Women\u2019s Health, University of Minnesota, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,10,30]]},"reference":[{"issue":"3","key":"e_1_3_4_2_2","first-page":"490","article-title":"Intrauterine growth restriction","author":"Resnik R","year":"2002","unstructured":"Resnik R. 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