{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:36:29Z","timestamp":1777876589687,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Perinatal stroke is an acute focal brain infarction or haemorrhage occurring from birth to 28 postnatal days. Perinatal stroke typically presents with seizures within 72\u00a0h and conversely hypoxic-ischaemic encephalopathy (HIE) presents at birth with signs of encephalopathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case<\/jats:title>\n                    <jats:p>This case report presents a case of perinatal stroke which was initially treated as HIE. The mother presented in labour and had thick meconium-stained liquor. The patient was born with a poor Apgar score and metabolic acidosis. The patient did not fulfil criteria for cooling therapy, until he developed a focal seizure at 7\u00a0h of life. Subsequently, therapeutic hypothermia (TH) therapy was initiated with the diagnosis of neonatal encephalopathy. However, a Magnetic Resonance Imaging (MRI) of the brain performed later showed left posterior cerebral artery territory subacute infarct with haemorrhagic component at the left occipital lobe.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The pathophysiology of perinatal stroke is similar to HIE which may lead to similar presentation at birth. Due to the difficulty in differentiating these two diseases, initiating therapeutic hypothermia for HIE is appropriate in this case. Utilisation of scoring tools may aid objective interpretation of MRI findings and prognostication of HIE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19345798251374939","type":"journal-article","created":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T09:15:11Z","timestamp":1756890911000},"page":"114-120","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Hypoxic-ischaemic encephalopathy, perinatal stroke or both? A case report"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0713-4322","authenticated-orcid":false,"given":"Adilah W.","family":"Ab Rahim","sequence":"first","affiliation":[{"name":"Universiti Sains Islam Malaysia"},{"name":"Hospital Ampang"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0500-2385","authenticated-orcid":false,"given":"Assyifaa","family":"bt Nik Mazian","sequence":"additional","affiliation":[{"name":"Hospital Ampang"},{"name":"Hospital Ampang"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Halimah","family":"Binti Abdul Halim","sequence":"additional","affiliation":[{"name":"Universiti Sains Islam Malaysia"},{"name":"Hospital Ampang"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8288-5647","authenticated-orcid":false,"given":"Azie Jumaatul Adawiyah","family":"Nabir","sequence":"additional","affiliation":[{"name":"Universiti Sains Islam Malaysia"},{"name":"Hospital Ampang"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3590-5964","authenticated-orcid":false,"given":"Siti Khadijah","family":"Mazli","sequence":"additional","affiliation":[{"name":"Universiti Sains Islam Malaysia"},{"name":"Hospital Ampang"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6127-7180","authenticated-orcid":false,"given":"Aliyyah","family":"Mohammad Khuzaini","sequence":"additional","affiliation":[{"name":"Universiti Sains Islam Malaysia"},{"name":"Hospital Ampang"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,3]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000183"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(04)00679-9"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090106"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000129909.77753.C4"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000001631"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.10.872"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1148"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/0883073807304200"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.02.064"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2020.11.015"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12658-X"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2021.101272"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.547281"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.12.04030"},{"issue":"2","key":"e_1_3_5_16_2","doi-asserted-by":"crossref","first-page":"e0247229","DOI":"10.1371\/journal.pone.0247229","article-title":"Effects of therapeutic hypothermia on death among asphyxiated neonates with hypoxic-ischemic encephalopathy: a systematic review and meta-analysis of randomized","volume":"16","author":"Abate BB","year":"2011","unstructured":"Abate BB, Bimerew M, Gebremichael B, et al. 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