{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T12:10:22Z","timestamp":1779019822600,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Bronchopulmonary dysplasia (BPD) remains one of the most common and serious complications of premature birth, often leading to long-term morbidities. It affects approximately 40\u201350% of infants born before 29\u00a0weeks of gestation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Our study was designed to validate the useful predictive value of serum NT-proBNP for BPD\/Death in preterm neonates born &lt;32\u00a0weeks of gestation with patent ductus arteriosus (PDA), in an Egyptian dual-center NICU setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Preterm neonates (&lt;32\u00a0weeks, &lt;72\u00a0h of age), regardless of PDA status, were prospectively enrolled. Echocardiographic assessment of PDA, including ductal diameter, was performed. NT-proBNP levels were measured twice during the first 10 days of life (within 72\u00a0hours and on days 8\u20139). At 36 weeks postmenstrual age, infants were classified into BPD\/death (n = 44) or survival without BPD (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 36).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>NT-proBNP levels measured within 72\u00a0hours and on days 8\u20139 showed a moderate predictive value for BPD\/death in infants with PDA diameter &gt;1.5\u00a0mm. At &lt;72\u00a0hours, the sensitivity was 62.8% and the specificity was 83.3%. At days 8\u20139, the sensitivity increased to 72.7% and the specificity to 88.9%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Serum NT-proBNP concentrations showed a moderate predictive value, with superior performance at days 8\u20139 of life for the development of BPD\/death in preterm infants, regardless of persistence of PDA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19345798261450454","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T11:41:31Z","timestamp":1778586091000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Serum NT-proBNP as a predictive biomarker for bronchopulmonary dysplasia and mortality in preterm infants with patent ductus arteriosus: A prospective validation study"],"prefix":"10.1177","author":[{"given":"Eman Rateb","family":"Abd Almonaem","sequence":"first","affiliation":[{"name":"Benha University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heba Rasmy","family":"Abdelbaset","sequence":"additional","affiliation":[{"name":"Benha University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2864-417X","authenticated-orcid":false,"given":"Amira Osama","family":"Abd El-Ghaffar","sequence":"additional","affiliation":[{"name":"Benha University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reham Samir","family":"Abd-el latif","sequence":"additional","affiliation":[{"name":"Benha University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman Gamal","family":"Abdelrahman","sequence":"additional","affiliation":[{"name":"Benha University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201812-2348OC"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-019-0127-7"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.08401"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12134207"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11030557"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1891\/0730-0832.36.5.265"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpeds.2023.100128"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines13030670"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-021-02750-9"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2017.00147"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.1896"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.4103\/jcn.jcn_189_20"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.25338.1"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2024.101565"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2024.1439265"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/biology11071034"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-025-02100-w"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-021-01475-w"},{"key":"e_1_3_6_20_2","first-page":"895","article-title":"Clinical study of bronchopulmonary dysplasia (BPD) in preterm neonates","volume":"15","author":"Hazarika K","year":"2025","unstructured":"Hazarika K, Desai R. Clinical study of bronchopulmonary dysplasia (BPD) in preterm neonates. Eur J Cardiovasc Med 2025; 15: 895\u2013899.","journal-title":"Eur J Cardiovasc Med"},{"key":"e_1_3_6_21_2","doi-asserted-by":"publisher","DOI":"10.3390\/jpm13091287"},{"key":"e_1_3_6_22_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11030667"}],"container-title":["Journal of Neonatal-Perinatal Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19345798261450454","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19345798261450454","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19345798261450454","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T11:41:34Z","timestamp":1779018094000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19345798261450454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,12]]},"references-count":21,"alternative-id":["10.1177\/19345798261450454"],"URL":"https:\/\/doi.org\/10.1177\/19345798261450454","relation":{},"ISSN":["1934-5798","1878-4429"],"issn-type":[{"value":"1934-5798","type":"print"},{"value":"1878-4429","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,12]]},"article-number":"19345798261450454"}}