{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T17:48:06Z","timestamp":1785779286686,"version":"3.56.0"},"reference-count":25,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:00:00Z","timestamp":1785456000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neonatal-Perinatal Medicine"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The prenatal \u201cdouble bubble\u201d (DB) sign is a marker of duodenal obstruction. When accompanied by distal bowel fluid on prenatal imaging, concern may arise for malrotation with volvulus. This study evaluated whether distal bowel fluid in fetuses with a prenatal DB sign is associated with malrotation or volvulus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed an 11-year retrospective review (Jan 2015\u2013Dec 2025) of fetuses with a prenatal DB sign evaluated at a single tertiary care center. Prenatal ultrasound and fetal MRI findings, operative diagnoses, and neonatal outcomes were reviewed, with specific attention to distal bowel fluid on fetal MRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-nine fetuses were identified. Median gestational age at birth was 37.5 weeks (IQR 34.5\u201338.0), and polyhydramnios was present in 62.1%. Fetal MRI was performed in 10 cases, demonstrating distal bowel fluid in 5. No prenatal imaging suggested volvulus. Among 27 neonates undergoing surgery, duodenal obstruction was confirmed in 25 (93.8%). Asymptomatic malrotation was identified in 5 infants, and no cases of prenatal or postnatal midgut volvulus occurred. One-year survival was 100%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Prenatal DB is a highly sensitive marker of duodenal obstruction. Distal bowel fluid on fetal MRI was not associated with malrotation with volvulus, supporting reassurance during prenatal counseling.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19345798261475329","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T10:47:34Z","timestamp":1785494854000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prenatal double bubble with distal fluid: Not a marker for malrotation with volvulus"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4141-275X","authenticated-orcid":false,"given":"Caitlin J.","family":"Cain-Trivette","sequence":"first","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3516-6719","authenticated-orcid":false,"given":"Christopher","family":"Nemeh","sequence":"additional","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3224-3204","authenticated-orcid":false,"given":"Yeu Sanz","family":"Wu","sequence":"additional","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-3467-8720","authenticated-orcid":false,"given":"Brooks","family":"Melnyk","sequence":"additional","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3067-7245","authenticated-orcid":false,"given":"Jooyoung P.","family":"Park","sequence":"additional","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn L.","family":"Simpson","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Duron","sequence":"additional","affiliation":[{"name":"Columbia University Vagelos College of Physicians and Surgeons \/ NewYork-Presbyterian Morgan Stanley Children\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,31]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2019-317085"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2021.1874338"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjpso.2023.100011"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1159\/000500471"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina61020171"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2023.02.029"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.21037\/qims-24-445"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.epsc.2023.102654"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.21037\/qims-22-37"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2015.16.6.1240"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.06.066"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-014-2896-1"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.6083"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5392"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-024-01984-6"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2024.1442866"},{"issue":"7","key":"e_1_3_6_18_2","first-page":"540","article-title":"Amniotic fluid volume assessment with the four-quadrant technique at 36-42 weeks\u2019 gestation","volume":"32","author":"Phelan JP","year":"1987","unstructured":"Phelan JP, Smith CV, Broussard P, et al. 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