{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:51:56Z","timestamp":1777877516568,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T00:00:00Z","timestamp":1585094400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"National Institute of Health","award":["5K23NS105935-02"],"award-info":[{"award-number":["5K23NS105935-02"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Neurohospitalist"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>Familial Mediterranean fever (FMF) is a rare autoinflammatory disorder of the innate immune system. Patients with innate immune system defects are at a high risk of meningococcal disease, although it is unclear if patients with FMF also have increased susceptibility to invasive infection. Herein, we present a diagnostically challenging case of a male adolescent with a past medical history of FMF stabilized on colchicine who presented with some of the early clinical features of community\u2014acquired bacterial meningitis. To our knowledge, this is the first case of meningococcal meningitis in a patient with FMF diagnosed with the FilmArray Meningitis\/Encephalitis (ME) Panel. This case report demonstrates that rapid detection of Neisseria meningitidis by the ME Panel can aid in the early diagnosis and prompt treatment of patients with suspected meningitis and may be the only positive test in patients with early presentation and\/or prior antimicrobial therapy.<\/jats:p>","DOI":"10.1177\/1941874420908421","type":"journal-article","created":{"date-parts":[[2020,3,25]],"date-time":"2020-03-25T05:13:11Z","timestamp":1585113191000},"page":"297-300","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Rapid Diagnosis of Meningococcal Meningitis in a Patient With Familial Mediterranean Fever by the FilmArray Meningitis\/Encephalitis Panel: A Case Report"],"prefix":"10.1177","volume":"10","author":[{"given":"Jyoti V.","family":"Ankam","sequence":"first","affiliation":[{"name":"Department of Biostatistics, Columbia University Mailman School of Public Health, Columbia University Irving Medical Center, New York, NY, USA"},{"name":"Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Torres","sequence":"additional","affiliation":[{"name":"Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanya A.","family":"Halse","sequence":"additional","affiliation":[{"name":"Meningitis Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen M.","family":"Canfield","sequence":"additional","affiliation":[{"name":"Department of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neville D.","family":"Clynes","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0050-0323","authenticated-orcid":false,"given":"Kiran T.","family":"Thakur","sequence":"additional","affiliation":[{"name":"Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel A.","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,3,25]]},"reference":[{"key":"bibr1-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1080\/13497413.2018.1481579"},{"key":"bibr2-1941874420908421","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00456"},{"key":"bibr3-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1016\/0887-8994(93)90068-N"},{"issue":"77","key":"bibr4-1941874420908421","first-page":"S127","volume":"31","author":"Capron J","year":"2013","journal-title":"Clin Exp Rheumatol"},{"key":"bibr5-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/320309"},{"key":"bibr6-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1980.03310130047029"},{"key":"bibr7-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00730-16"},{"key":"bibr8-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01927-17"},{"key":"bibr9-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2006.02.016"},{"key":"bibr10-1941874420908421","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.2.475"},{"key":"bibr11-1941874420908421","doi-asserted-by":"publisher","DOI":"10.4161\/viru.26515"}],"container-title":["The Neurohospitalist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1941874420908421","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1941874420908421","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1941874420908421","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:53:31Z","timestamp":1777589611000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1941874420908421"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,25]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1177\/1941874420908421"],"URL":"https:\/\/doi.org\/10.1177\/1941874420908421","relation":{},"ISSN":["1941-8744","1941-8752"],"issn-type":[{"value":"1941-8744","type":"print"},{"value":"1941-8752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,25]]}}}