{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:53:37Z","timestamp":1777877617394,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T00:00:00Z","timestamp":1695168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Neurohospitalist"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Wilson\u2019s Disease (WD) manifests with systemic and neuropsychiatric symptoms, caused by an ATP7B genetic mutation, leading to an accumulation of copper. Presentations are diverse and the diagnosis should be considered in anyone under 50 with a new onset movement disorder. Early recognition and treatment can limit morbidity. While liver transplantation (LT) is recommended in WD patients with hepatic failure, its use for pure neurologic indication remains controversial. We present a patient who failed medical management and underwent LT for pure neurologic indications. Subsequent neurologic symptom improvement supports the use of LT for patients with pure neurologic manifestations of WD.<\/jats:p>","DOI":"10.1177\/19418744231203277","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T05:51:25Z","timestamp":1695189085000},"page":"99-103","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Treating the Neurologic Manifestations of Wilson\u2019s Disease With Liver Transplantation"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-7685-0818","authenticated-orcid":false,"given":"Sarah","family":"Marmol","sequence":"first","affiliation":[{"name":"University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul Walker","family":"Maeder-York","sequence":"additional","affiliation":[{"name":"University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Hislop","sequence":"additional","affiliation":[{"name":"Miami VA Healthcare System, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielle S.","family":"Shpiner","sequence":"additional","affiliation":[{"name":"University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8976-2500","authenticated-orcid":false,"given":"Jason","family":"Margolesky","sequence":"additional","affiliation":[{"name":"University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"key":"bibr2-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2012.02.041"},{"key":"bibr3-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27641"},{"key":"bibr4-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0018-3"},{"key":"bibr5-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000085871.98174.4E"},{"key":"bibr6-19418744231203277","doi-asserted-by":"publisher","DOI":"10.5223\/pghn.2015.18.3.187"},{"key":"bibr7-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29292"},{"key":"bibr8-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21693"},{"key":"bibr9-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-022-01872-w"},{"key":"bibr10-19418744231203277","first-page":"1","volume":"13","author":"Ziemssen T","year":"2022","journal-title":"Acta Neurol Belg"},{"key":"bibr11-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1007\/s40261-022-01117-x"},{"key":"bibr12-19418744231203277","unstructured":"ClinicalTrials.gov: Study of UX701 gene transfer for the treatment of Wilson disease. (cited 2023 Mar 17). Available from: Study_of_UX701_Gene_Transfer_for_the_Treatment_of_Wilson_Disease_-_Full_Text_View_-_ClinicalTrials.gov"},{"key":"bibr1-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8278(95)80194-4"},{"key":"bibr13-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1002\/hep.32801"},{"key":"bibr14-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000009474"},{"key":"bibr15-19418744231203277","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27288"}],"container-title":["The Neurohospitalist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19418744231203277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19418744231203277","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19418744231203277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:56:45Z","timestamp":1777589805000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19418744231203277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,20]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1177\/19418744231203277"],"URL":"https:\/\/doi.org\/10.1177\/19418744231203277","relation":{},"ISSN":["1941-8744","1941-8752"],"issn-type":[{"value":"1941-8744","type":"print"},{"value":"1941-8752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,20]]}}}