{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T06:02:26Z","timestamp":1785564146468,"version":"3.56.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Neurohospitalist"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:p>Anti-leucine rich glioma inactivated 1 (LGI-1) autoimmune encephalitis (AE) typically presents with cognitive impairment, faciobrachial dystonic seizures (FBDS) and hyponatraemia. Reports are growing of neurological complications following coronavirus disease 2019 (COVID-19) vaccination. Here we describe a 50 year old man who developed anti-LGI-1 limbic encephalitis and autoimmune epilepsy 4 days following a dose of the mRNA Pfizer COVID-19 vaccine (of note, his first two vaccinations were viral vector ChAdOX1-S). He presented with focal aware seizures characterised by short-lived episodes of confusion, emotional distress and d\u00e9j\u00e0 vu associated with palpitations. He also reported subacute progressive amnesia. He responded well to high-dose steroid and subsequent immunoglobulin therapy. To our knowledge, this is the first reported case of anti-LGI-1 AE following a mixed COVID-19 vaccination regimen. We aim to complement the early literature on this post-COVID-19 vaccination phenomenon.<\/jats:p>","DOI":"10.1177\/19418744241234100","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T19:14:30Z","timestamp":1708456470000},"page":"332-335","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Anti-LGI-1 Limbic Encephalitis and Autoimmune Epilepsy Following a Third Dose of COVID-19 Vaccination: A Case Report"],"prefix":"10.1177","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-8760-4820","authenticated-orcid":false,"given":"Gerry","family":"Mullan","sequence":"first","affiliation":[{"name":"Royal Victoria Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5351-7313","authenticated-orcid":false,"given":"Michael","family":"Kinney","sequence":"additional","affiliation":[{"name":"Royal Victoria Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40001-023-00992-0"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09590-9"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.813487"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-022-11234-4"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcad060"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s42466-022-00187-8"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000903244.59854.3a"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2020-002567"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2022.18.6.692"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22307"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra1708712"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2022.5346"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awy010"},{"key":"e_1_3_3_16_2","volume-title":"Public Health Impact of Covid-19 Vaccines in the US: Observational Study","author":"Suthar AB","year":"2022","unstructured":"Suthar AB, Wang J, Seffren V, Wiegand RE, Griffing S, Zell E. 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