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Magnetic resonance brain imaging demonstrated a large left frontal lesion with parenchymal contrast enhancement. Magnetic resonance spectroscopy indicated elevated choline to creatine and choline to N-acetyl aspartate ratios, further suggestive of high-grade glioma. However, subsequent biopsy findings revealed perivascular amyloid deposits, confirming the diagnosis of CAA-ri. To our knowledge, this is the first case in literature to report elevated choline to creatine and choline to N-acetyl aspartate ratios in cerebral amyloid angiopathy-related inflammation.<\/jats:p>","DOI":"10.1177\/19418744241296198","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T23:48:18Z","timestamp":1729727298000},"page":"216-220","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["CAA-ri Masquerading as a High-Grade Glioma: A Case Report"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0751-792X","authenticated-orcid":false,"given":"Angela","family":"Xia","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Neurology, University of Kentucky College of Medicine, Lexington, Kentucky, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Andreev","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra Northwell, Hempstead, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Regenhardt","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Harvard Medical School\/Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,10,23]]},"reference":[{"key":"bibr1-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.10.2073"},{"key":"bibr2-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000510"},{"key":"bibr3-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000012778"},{"key":"bibr4-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10810"},{"key":"bibr5-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.1782"},{"key":"bibr6-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2015.4078"},{"key":"bibr7-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(22)00208-3"},{"key":"bibr8-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.002267"},{"key":"bibr9-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181dad605"},{"key":"bibr10-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002444"},{"key":"bibr11-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000003613"},{"key":"bibr12-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1111\/nan.12946"},{"key":"bibr13-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.13130531"},{"key":"bibr14-19418744241296198","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14133197"},{"key":"bibr15-19418744241296198","first-page":"1705","volume":"25","author":"Safriel Y","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr16-19418744241296198","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2008.07.002"}],"container-title":["The Neurohospitalist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19418744241296198","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19418744241296198","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19418744241296198","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:57:43Z","timestamp":1777589863000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19418744241296198"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,23]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1177\/19418744241296198"],"URL":"https:\/\/doi.org\/10.1177\/19418744241296198","relation":{},"ISSN":["1941-8744","1941-8752"],"issn-type":[{"value":"1941-8744","type":"print"},{"value":"1941-8752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,23]]}}}