{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:54:06Z","timestamp":1777877646803,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T00:00:00Z","timestamp":1733702400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100016646","name":"HCA Healthcare","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100016646","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Neurohospitalist"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>\n                    Cryptococcal meningitis is a leading cause of morbidity and mortality in patients infected with human immunodeficiency virus. In over 90% of cases, it occurs at CD4 T lymphocyte (CD4) cell counts of less than 100 cells\/mm\n                    <jats:sup>3<\/jats:sup>\n                    . Cryptococcomas are rare granulomatous lesions that can occur in disseminated central nervous system cryptococcal infection, primarily in immunocompetent hosts. Here we report a case of disseminated cryptococcal meningitis with numerous cryptococcomas mimicking metastases in a patient with HIV and a CD4 count of 115. The patient\u2019s serum and cerebrospinal fluid (CSF) cryptococcal antigen, CSF cryptococcal polymerase chain reaction, and serum and CSF cryptococcal cultures were all negative. Brain biopsy pathology confirmed the diagnosis. In this paper, we highlight the importance of early cerebral biopsy in the diagnosis and management of cryptococcoma.\n                  <\/jats:p>","DOI":"10.1177\/19418744241307413","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T08:50:27Z","timestamp":1733734227000},"page":"308-312","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Multiple Central Nervous System Cryptococcomas Masquerading as Lymphoma"],"prefix":"10.1177","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8129-3831","authenticated-orcid":false,"given":"Alexander V.","family":"Ortiz","sequence":"first","affiliation":[{"name":"Department of Radiology, Stanford University Medical Center, Stanford, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6495-9128","authenticated-orcid":false,"given":"Dhruven","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, TriStar Centennial Medical Center, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juli","family":"Horton","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, TriStar Centennial Medical Center, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9102-0768","authenticated-orcid":false,"given":"Adrian A.","family":"Jarquin-Valdivia","sequence":"additional","affiliation":[{"name":"Department of Neurology, TriStar Centennial Medical Center, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,12,9]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30243-8"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0056269"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/313992"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2016.09.016"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2016-218824"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1590\/1516-3180.2017.0046210417"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-020-01880-4"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.25259\/SNI_1243_2021"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy602"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.4103\/2156-7514.184010"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1590\/0100-3984.2016.0017"},{"issue":"3","key":"e_1_3_5_13_2","first-page":"430","article-title":"A spuriously negative cryptococcal antigen assay result in disseminated cryptococcosis: the deception of the postzone phenomenon","volume":"51","author":"Malik AAA","year":"2021","unstructured":"Malik AAA, Periyasamy P, Kori N, Wahab AA, Ding CH. A spuriously negative cryptococcal antigen assay result in disseminated cryptococcosis: the deception of the postzone phenomenon. 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