{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:10:29Z","timestamp":1788667829947,"version":"build-2803163510"},"reference-count":15,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["The Neurohospitalist"],"abstract":"<jats:sec>\n                    <jats:title>Background\/Purpose<\/jats:title>\n                    <jats:p>Downbeat nystagmus (DBN) is an uncommon finding in comatose patients, especially as a manifestation of epileptiform activity. We report a 59-year-old man who developed DBN in the context of myoclonic status epilepticus following anoxic brain injury secondary to cardiac arrest. The DBN was phase-locked with generalized periodic epileptiform discharges (GPDs) on electroencephalography (EEG) and resolved with pharmacologic burst suppression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This case suggests a potential link between DBN and cortical epileptiform activity, which we hypothesize may be due to bilateral cortical hyperexcitability and cerebellar disinhibition. The presence of DBN in this setting may indicate a poor prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19418744261477539","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:04:43Z","timestamp":1788451483000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Downbeat Nystagmus as a Manifestation of Myoclonic Status Epilepticus in a Patient With Anoxic Brain Injury"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7873-9480","authenticated-orcid":false,"given":"T. Maxwell","family":"Parker","sequence":"first","affiliation":[{"name":"Departments of Neurology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott N.","family":"Grossman","sequence":"additional","affiliation":[{"name":"Departments of Neurology, New York University Grossman School of Medicine, New York, NY, USA"},{"name":"Department of Ophthalmology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura J.","family":"Balcer","sequence":"additional","affiliation":[{"name":"Departments of Neurology, New York University Grossman School of Medicine, New York, NY, USA"},{"name":"Department of Ophthalmology, New York University Grossman School of Medicine, New York, NY, USA"},{"name":"Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven L.","family":"Galetta","sequence":"additional","affiliation":[{"name":"Departments of Neurology, New York University Grossman School of Medicine, New York, NY, USA"},{"name":"Department of Ophthalmology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet C.","family":"Rucker","sequence":"additional","affiliation":[{"name":"Departments of Neurology, New York University Grossman School of Medicine, New York, NY, USA"},{"name":"Department of Ophthalmology, New York University Grossman School of Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebcr.2014.08.004"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.2.340"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1059-1311(03)00100-6"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090418"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000125184.88797.62"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5153-z"},{"key":"e_1_3_5_8_2","first-page":"149","article-title":"Selective vulnerability in brain hypoxia","volume":"6","author":"Cerv\u00f3s-Navarro J","year":"1991","unstructured":"Cerv\u00f3s-Navarro J, Diemer NH. 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Crit Rev Neurobiol. 1991;6:149-182.","journal-title":"Crit Rev Neurobiol"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.46.4.1086"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410200313"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2018.01.007"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090216"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1981.00510050063010"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/19418744251331649"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.12.1109"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-023-03311-6"}],"container-title":["The Neurohospitalist"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19418744261477539","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19418744261477539","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19418744261477539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T03:26:55Z","timestamp":1788665215000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19418744261477539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,3]]},"references-count":15,"alternative-id":["10.1177\/19418744261477539"],"URL":"https:\/\/doi.org\/10.1177\/19418744261477539","relation":{},"ISSN":["1941-8744","1941-8752"],"issn-type":[{"value":"1941-8744","type":"print"},{"value":"1941-8752","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,3]]},"article-number":"19418744261477539"}}