{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:31:35Z","timestamp":1787311895614,"version":"build-2736575974"},"reference-count":34,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Respiratory Care"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Amyotrophic lateral sclerosis (ALS) is a fatal heterogeneous neurodegenerative disease characterized by the degeneration of both upper and lower motor neurons and spinal cord. Measurement of respiratory muscle strength has been shown to be an important assessment in the decision-making process and can be assessed by maximum inspiratory (P\n                      <jats:sub>Imax<\/jats:sub>\n                      ) and expiratory pressures (P\n                      <jats:sub>Emax<\/jats:sub>\n                      ), sniff nasal inspiratory (SNIP) and expiratory (SNEP) pressures. Body position appears to have a significant effect on respiratory muscle strength. The aim of this study was to observe the difference in peak values of SNIP and SNEP of the respiratory muscles measured in 2 different positions (seated and supine with 45\u00b0 elevation) in subjects with ALS and a group of matched healthy subjects.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This is a case\u2013control study of subjects with ALS and healthy subjects. Spirometry and surface electromyography (EMG) of the sternocleidomastoid, scalene, rectus abdominis, and external oblique muscles were assessed during P\n                      <jats:sub>Imax<\/jats:sub>\n                      and P\n                      <jats:sub>Emax<\/jats:sub>\n                      maneuvers in the seated position, and SNIP and SNEP in the seated and supine positions at 45\u00b0 elevation (randomized).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      SNEP values in the 45\u00b0 elevation were lower than in the sitting position in ALS (70.3 \u00b1 26.7 vs 57.3 \u00b1 22.8\u2009cm H\n                      <jats:sub>2<\/jats:sub>\n                      O,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .041). SNIP and SNEP were lower in ALS in the 45\u00b0 elevation compared with healthy subjects (69.1 \u00b1 27.2 vs 95.5 \u00b1 23.5\u2009cm H\n                      <jats:sub>2<\/jats:sub>\n                      O; 57.3 \u00b1 22.5 vs 92.7 \u00b1 26.4\u2009cm H\n                      <jats:sub>2<\/jats:sub>\n                      O,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .041). In subjects with ALS, baseline electromyographic activity of the sternocleidomastoid muscle at rest was higher than in healthy subjects in both positions (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .041). No significant differences in electrical activity were found for other variables and measurements.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In ALS, nasal pressure may be affected by reduced diaphragm and abdominal muscle effectiveness in the supine position. The sternocleidomastoid muscle showed increased electrical activity in the supine position with 45\u00b0 elevation compared with controls, which may indicate muscle weakness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19433654251389828","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T16:31:37Z","timestamp":1764347497000},"page":"307-314","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Body Position on Respiratory Pressure and Muscle Activity in Amyotrophic Lateral Sclerosis and Healthy Subjects"],"prefix":"10.1177","volume":"71","author":[{"given":"Ana Cristina de Medeiros Garcia","family":"Maciel","sequence":"first","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Aline Marcelino","family":"da Silva","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9ssica Danielle","family":"Medeiros da Fonseca","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rayane Grayce da Silva","family":"Vieira","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lailane Saturnino","family":"da Silva","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiago Bezerra Wanderley e","family":"Lima","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen de Medeiros","family":"Pondofe","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mat\u00edas","family":"Otto-Y\u00e1\u00f1ez","sequence":"additional","affiliation":[{"name":"Dr. Otto-Ya\u00f1ez is affiliated with the Escuela de Kinesiologia Universidad Autonoma de Chile, Campus Providencia, Santiago, Santiago Onofre Lopes University Hospital, Metropolitan Region, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Torres-Castro","sequence":"additional","affiliation":[{"name":"Drs. Torres-Castro and Vera Uribe is affiliated with the Departamento de Kinesiolog\u00eda, Universidad de Chile, Santiago de Chile, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Vera-Uribe","sequence":"additional","affiliation":[{"name":"Drs. Torres-Castro and Vera Uribe is affiliated with the Departamento de Kinesiolog\u00eda, Universidad de Chile, Santiago de Chile, Chile."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Vilar\u00f3","sequence":"additional","affiliation":[{"name":"Dr Vilar\u00f3 is affiliated with the Blanquerna Faculty of Health Sciences, GRoW: Global Research on Wellbeing, Ramon Llull University, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario Emilio Teixeira","family":"Dourado Junior","sequence":"additional","affiliation":[{"name":"Dr. Dourado Junior is affiliated with the Departamento de Medicina Integrada, Hospital Universit\u00e1rio Onofre Lopes, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa Regiane","family":"Resqueti","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Augusto de Freitas","family":"Fregonezi","sequence":"additional","affiliation":[{"name":"Ms. Maciel, Ms. da Silva, Dr. da Fonseca, Ms. da Silva Vieira, Ms. da Silva, Ms. Lima, Dr. Pondofe, Dr. Resqueti, and Dr. Fregonezi are affiliated with the Pneumocardiovascular Lab\/HUOL and the Laborat\u00f3rio de Inova\u00e7\u00e3o Tecnol\u00f3gica em Reabilita\u00e7\u00e3o, Departamento de Fisioterapia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31287-4"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-385157-4.00608-4"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2011.153"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.03.039"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2017.3339"},{"issue":"3","key":"e_1_3_4_7_2","first-page":"131","article-title":"Pulmonary function tests in patients with amyotrophic lateral sclerosis and the association between these tests and survival","volume":"13","author":"Javad Mousavi S-A","year":"2014","unstructured":"Javad Mousavi S-A, , Zamani B, , Shahabi Shahmiri S, et al. 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