{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:29:52Z","timestamp":1777386592320,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T00:00:00Z","timestamp":1592179200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100003572","name":"American Academy of Otolaryngic Allergy Foundation","doi-asserted-by":"publisher","award":["2019 AAOAF Research Award"],"award-info":[{"award-number":["2019 AAOAF Research Award"]}],"id":[{"id":"10.13039\/100003572","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Allergic fungal rhinosinusitis (AFRS) is disproportionately identified in patients of low socioeconomic status living in warm, humid climates, and is thought to occur in response to environmental fungal species.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We hypothesized that micro-geographic differences in fungal exposure contribute to the pathogenesis of AFRS, and compared home fungal exposure of patients with AFRS to normative data and controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Comprehensive prospective enrollment and data capture was completed in 70 patients. Patients with AFRS were compared to a control population with chronic rhinosinusitis with nasal polyposis (CRSwNP) and comorbid atopy. Comprehensive demographics, 22-item sino-nasal outcomes test (SNOT-22) questionnaires, and endoscopy scores were compiled. Using a test strip collection system, a home fungal assessment was completed for each patient, along with detailed questions related to home condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients with AFRS were more likely to be younger (p&lt;.001), African American (p&lt;.001), from a lower income bracket (p\u2009&lt;\u2009.012), and less likely to own their home (p\u2009&lt;\u2009.001). There were no differences in prior surgeries (p=.432), endoscopy scores (p\u2009=\u2009.409) or SNOT-22 scores (p\u2009=\u2009.110) between the groups. There were no differences in overall fungal counts between patients with AFRS and controls (p\u2009=\u2009.981). AFRS patients had a higher prevalence of Basidiospores than controls (p\u2009=\u2009.034).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study failed to detect differences in total home fungal exposure levels between those with AFRS and atopic CRSwNP, despite differences in socioeconomic status. This suggests that absolute fungal levels may not be the primary driver in development of AFRS, or that the fungal detection strategies utilized were not representative of patients\u2019 overall fungal exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1945892420930953","type":"journal-article","created":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T21:54:09Z","timestamp":1592258049000},"page":"784-791","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["The Role of Home Fungal Exposure in Allergic Fungal Rhinosinusitis"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1296-2648","authenticated-orcid":false,"given":"Nicholas R.","family":"Rowan","sequence":"first","affiliation":[{"name":"Division of Rhinology and Sinus Surgery, Department of Otolaryngology \u2013 Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina"},{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristina A.","family":"Storck","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Sinus Surgery, Department of Otolaryngology \u2013 Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodney J.","family":"Schlosser","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Sinus Surgery, Department of Otolaryngology \u2013 Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina"},{"name":"Department of Surgery, Ralph H. Johnson VA Medical Center, Charleston, South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary M.","family":"Soler","sequence":"additional","affiliation":[{"name":"Division of Rhinology and Sinus Surgery, Department of Otolaryngology \u2013 Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,6,15]]},"reference":[{"key":"bibr1-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(00)80018-3"},{"key":"bibr2-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.10.020"},{"key":"bibr3-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2449-5"},{"key":"bibr4-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1177\/1179550619870758"},{"key":"bibr5-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12314"},{"key":"bibr6-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1016\/j.wjorl.2018.08.003"},{"key":"bibr7-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1080\/13693780802314809"},{"key":"bibr8-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2014-006680"},{"key":"bibr9-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200106000-00015"},{"key":"bibr10-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26248"},{"key":"bibr11-1945892420930953","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2010.24.3533"},{"key":"bibr12-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815580978"},{"key":"bibr13-1945892420930953","doi-asserted-by":"publisher","DOI":"10.3109\/02770903.2014.905593"},{"key":"bibr14-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.11.027"},{"key":"bibr15-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2004.00596.x"},{"key":"bibr16-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2015.04.002"},{"key":"bibr17-1945892420930953","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2013.301253"},{"key":"bibr18-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1177\/019459989411100508"},{"issue":"1","key":"bibr19-1945892420930953","first-page":"S3","volume":"6","author":"Orlandi RR","year":"2016","journal-title":"Int Forum Allergy Rhinol"},{"key":"bibr20-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1177\/000348949510410s02"},{"key":"bibr21-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4486.2006.01155.x"},{"key":"bibr22-1945892420930953","first-page":"13","volume":"21","author":"Sahay R.","year":"2008","journal-title":"Indian J Aerobiol"},{"key":"bibr23-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21292"},{"key":"bibr24-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21077"},{"key":"bibr25-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21298"},{"key":"bibr26-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e31812e01ab"},{"key":"bibr27-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1126\/science.1240342"},{"key":"bibr28-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-017-4717-2"},{"key":"bibr29-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21295"},{"key":"bibr30-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.12.053"},{"key":"bibr31-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1177\/1945892419825695"},{"key":"bibr32-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1038\/nri3538"},{"key":"bibr33-1945892420930953","doi-asserted-by":"publisher","DOI":"10.1021\/es501489u"}],"container-title":["American Journal of Rhinology &amp; Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1945892420930953","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1945892420930953","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1945892420930953","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T09:36:40Z","timestamp":1777369000000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1945892420930953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,15]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1177\/1945892420930953"],"URL":"https:\/\/doi.org\/10.1177\/1945892420930953","relation":{},"ISSN":["1945-8924","1945-8932"],"issn-type":[{"value":"1945-8924","type":"print"},{"value":"1945-8932","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,15]]}}}