{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:25:45Z","timestamp":1777386345127,"version":"3.51.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The short-term adverse events and predictors of morbidity in surgical resection of esthesioneuroblastoma (ENB) are largely unknown, and investigating these variables can help direct planning for at-risk patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The 2005\u20132017 National Surgical Quality Improvement Program database was queried to identify patients with a diagnosis of ENB undergoing skull base surgery for tumor resection. Information regarding demographics, patient morbidity score, pre-operative and intra-operative data, and post-operative outcomes were extracted. Cox proportional hazard analysis was utilized to assess complication and readmission\/reoperation rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 95 patients undergoing skull base surgery for resection of ENB were included. Mean age, BMI, operation time, and post-operative length of stay (LOS) of the cohort were 53.6\u2009\u00b1\u200916.2\u2009years, 29.1\u2009\u00b1\u20096.5, 392.0\u2009\u00b1\u2009204.6\u2009minutes, and 5.8\u2009\u00b1\u20094.6\u2009days, respectively. In total, 31 patients (32.6%) experienced at least one 30-day adverse event, which included blood transfusion intra-operatively or within 72\u2009hours from the operation (22.1%), readmission (10.7%), intubation &gt;48\u2009hours (7.4%), reintubation (4.2%), organ or space infection (4.2%), reoperation (4.0%), superficial or deep surgical site infection (2.1%), sepsis (2.1%), pulmonary embolism (1.1%), and myocardial infarction (1.1%). Patients who experienced at least one adverse event had significantly higher operation time (486.8\u2009\u00b1\u2009230.4 vs. 347.5\u2009\u00b1\u2009176.2\u2009minutes, p\u2009=\u20090.002), LOS (9.2\u2009\u00b1\u20095.6\u2009days vs. 4.2\u2009\u00b1\u20093.0, p\u2009&lt;\u20090.001), and lower hematocrit (37.3\u2009\u00b1\u20095.9 vs. 41.2\u2009\u00b1\u20093.8, p\u2009&lt;\u20090.001) and albumin levels (3.8\u2009\u00b1\u20090.6 vs. 4.2\u2009\u00b1\u20090.3, p\u2009=\u20090.009). Patients with a higher American Society of Anesthesiologists (ASA) score (HR\u2009=\u20092.39; p\u2009=\u20090.047) or longer operation time (HR\u2009=\u20091.004; p\u2009=\u20090.001) had a significantly higher risk for experiencing adverse events. Obesity was not associated with different intra- or post-operative outcomes, but older patients had shorter operations ( p\u2009=\u20090.002) and LOS ( p\u2009=\u20090.0014).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Longer operation time and lower pre-operative hematocrit and albumin levels may all increase complication rates in ENB resection. Patients with high ASA score or more advanced age may have different short-term outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1945892420970468","type":"journal-article","created":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:42:52Z","timestamp":1604018572000},"page":"500-506","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Short-Term Morbidity and Predictors of Adverse Events Following Esthesioneuroblastoma Surgery"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0045-2547","authenticated-orcid":false,"given":"Khodayar","family":"Goshtasbi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2133-7708","authenticated-orcid":false,"given":"Jack L.","family":"Birkenbeuel","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3585-698X","authenticated-orcid":false,"given":"Mehdi","family":"Abouzari","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon M.","family":"Lehrich","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8482-0369","authenticated-orcid":false,"given":"Tyler M.","family":"Yasaka","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2656-1060","authenticated-orcid":false,"given":"Arash","family":"Abiri","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6556-4507","authenticated-orcid":false,"given":"Ethan G.","family":"Muhonen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, University of California, Irvine, California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank P. 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