{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:40:24Z","timestamp":1787506824257,"version":"build-2736575974"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T00:00:00Z","timestamp":1711584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Beijing Hospitals Authority Clinical Medicine Development of Special Funding","award":["XMLX202136"],"award-info":[{"award-number":["XMLX202136"]}]},{"name":"Key clinical projects of Peking University Third Hospital","award":["BYSYZD2023029"],"award-info":[{"award-number":["BYSYZD2023029"]}]},{"name":"Beijing Science and Technology Nova Program","award":["Z201100006820086"],"award-info":[{"award-number":["Z201100006820086"]}]},{"name":"Beijing Hospitals Authority Youth Program","award":["QML20190617"],"award-info":[{"award-number":["QML20190617"]}]},{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82000954"],"award-info":[{"award-number":["82000954"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Endoscopic sinus surgery (ESS) could significantly improve olfactory function among patients with chronic rhinosinusitis (CRS). This study aimed to perform a meta-analysis to evaluate the effect of ESS on the olfactory bulb volume (OBV) among patients with CRS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systemic search of PubMed, Medline, Embase, Web of Science, and other databases was conducted to identify studies assessing OBV changes in patients with CRS after ESS utilizing magnetic resonance imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of four studies with 168 participants were included. Comparing the changes in OBV of patients with CRS before and after surgery within 3-6 months, the ESS significantly improved the overall OBV ( P\u2009=\u20090.005, I\n                      <jats:sup>2\u2009<\/jats:sup>\n                      =\u200966%), with the left OBV increased by 5.57mm\n                      <jats:sup>3<\/jats:sup>\n                      ( P\u2009=\u20090.84, I\n                      <jats:sup>2\u2009<\/jats:sup>\n                      =\u20090%), and the right OBV increased by 8.63mm\n                      <jats:sup>3<\/jats:sup>\n                      ( P\u2009=\u20090.09, I\n                      <jats:sup>2\u2009<\/jats:sup>\n                      =\u200953%). A difference in OBV persists between healthy controls and patients with CRS 3-6 months after ESS. The overall OBV of patients with CRS after ESS was significantly smaller than controls (mean difference\u2009=\u2009-3.84, P\u2009=\u20090.04), with a mean difference of 4.13mm\n                      <jats:sup>3<\/jats:sup>\n                      on the left side ( P\u2009=\u20090.72, I\n                      <jats:sup>2\u2009<\/jats:sup>\n                      =\u20090%), and a mean difference of 3.22mm\n                      <jats:sup>3<\/jats:sup>\n                      on the right side ( P\u2009=\u20090.0001, I\n                      <jats:sup>2\u2009<\/jats:sup>\n                      =\u200989%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ESS significantly increases the OBV among patients with CRS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19458924241241874","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T02:34:56Z","timestamp":1711679696000},"page":"251-257","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Effects of Endoscopic Sinus Surgery on Olfactory Bulb Volume among Patients with Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"38","author":[{"given":"Xincen","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Peking University Third Hospital, Beijing, PR China"},{"name":"Department of Medicine, Peking University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianhao","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, The First Affiliated Hospital of Wenzhou Medical University, Zhejiang, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifan","family":"Chang","sequence":"additional","affiliation":[{"name":"Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Peking University Third Hospital, Beijing, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4888-3255","authenticated-orcid":false,"given":"Dawei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Peking University Third Hospital, Beijing, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,3,28]]},"reference":[{"key":"bibr1-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22929"},{"key":"bibr2-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.01.024"},{"key":"bibr3-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2019.08.011"},{"key":"bibr4-19458924241241874","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2008.22.3237"},{"key":"bibr5-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.134.6.621"},{"key":"bibr6-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21922"},{"key":"bibr7-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21478"},{"key":"bibr8-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp243"},{"key":"bibr9-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13202"},{"key":"bibr10-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2018.10.011"},{"key":"bibr11-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-19-07433.1997"},{"key":"bibr12-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2021.02.013"},{"key":"bibr13-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04364.x"},{"key":"bibr14-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1177\/19458924221140965"},{"key":"bibr15-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0403-19.2020"},{"key":"bibr16-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(03)00172-6"},{"key":"bibr17-19458924241241874","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2018.00050"},{"key":"bibr18-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.09.028"},{"key":"bibr19-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.01.016"},{"key":"bibr20-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.01.044"},{"key":"bibr21-19458924241241874","doi-asserted-by":"publisher","DOI":"10.1016\/S1076-6332(97)80027-X"}],"container-title":["American Journal of Rhinology &amp; 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