{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:01:23Z","timestamp":1792011683476,"version":"4.4.0"},"reference-count":44,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:00:00Z","timestamp":1744243200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol&amp;#65533;Allergy"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Orbital decompression is an essential tool for reducing proptosis in thyroid eye disease (TED), yet the impact of surgical approach and preoperative factors on outcomes remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare proptosis reduction following different orbital decompression techniques, identify additional risk factors that may play a role in surgical orbital decompression outcomes, and develop clinical decision-making recommendations based on these results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was performed on TED patients who underwent endoscopic medial wall, orbital floor, and\/or open lateral wall decompression. We evaluated the influence of preoperative comorbidities, anatomic and laboratory values, and surgical approach on postdecompression Hertel exophthalmometry outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Analysis encompassed 130 orbits from 80 patients, 83% female, 48 with preoperative diplopia, and mean age of 54.4 years. Preoperative Hertel measurement was predictive of extent of proptosis reduction (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.0001), indicating that higher initial Hertel measurement predicts greater absolute reduction following surgical intervention. Surgical technique correlated with outcome on univariate analysis (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.04), but not multivariate (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.13) analyses. When categorized into preoperative Hertel ranges, combined endoscopic medial and open lateral wall decompression resulted in mean proptosis reduction of 3.13\u2005mm for range 20.01 to 24\u2005mm and 3.85\u2005mm for range 24.01 to 28\u2005mm. Three-wall decompression resulted in mean proptosis reduction of 2.49\u2005mm for and 3.84\u2005mm for these ranges, respectively. Variables such as smoking, body mass index, orbital wall height, and TRAb level, did not affect outcomes. Nine patients had new onset diplopia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Preoperative Hertel exophthalmometry is the strongest predictor of proptosis reduction following orbital decompression in TED. Surgical technique appears to be less impactful on outcome than expected. Surgical decision making should be individualized based on patient goals; these findings can be used to achieve proptosis reduction and limit the risk of new onset diplopia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19458924251330947","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T06:50:16Z","timestamp":1744267816000},"page":"284-292","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Orbital Decompression for Thyroid Eye Disease: Outcomes by Preoperative Severity and Technique"],"prefix":"10.1177","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1378-9624","authenticated-orcid":false,"given":"Lazaro R.","family":"Peraza","sequence":"first","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4479-7639","authenticated-orcid":false,"given":"Forrest W.","family":"Fearington","sequence":"additional","affiliation":[{"name":"Mayo Clinic Alix School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel A.","family":"Hernandez-Herrerra","sequence":"additional","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Awadallah","sequence":"additional","affiliation":[{"name":"Mayo Clinic Alix School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilly H.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea A.","family":"Tooley","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Bradley","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius N.","family":"Stan","sequence":"additional","affiliation":[{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1402-7461","authenticated-orcid":false,"given":"Janalee K.","family":"Stokken","sequence":"additional","affiliation":[{"name":"Mayo Clinic"},{"name":"Mayo Clinic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.12472"},{"key":"e_1_3_3_3_2","article-title":"Teprotumumab-TRBW as a novel monoclonal antibody for thyroid eye disease: a literature review","volume":"15","author":"Bocklud BE","year":"2023","unstructured":"Bocklud BE, Fakhre W, Murphy B, et al. 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