{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:25:00Z","timestamp":1789586700475,"version":"build-2803163510"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T00:00:00Z","timestamp":1764720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Taiwan National Science and Technology Council","award":["114-2314-B-182 -031 -MY2"],"award-info":[{"award-number":["114-2314-B-182 -031 -MY2"]}]},{"DOI":"10.13039\/501100005795","name":"Chang Gung Memorial Hospital, Linkou","doi-asserted-by":"publisher","award":["CMRPG3P0571"],"award-info":[{"award-number":["CMRPG3P0571"]}],"id":[{"id":"10.13039\/501100005795","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol&amp;#65533;Allergy"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Subjective and objective evaluations of chronic rhinosinusitis with nasal polyps (CRSwNP) are often discordant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to investigate the feasibility of using a newly developed five-item Sino-Nasal Outcome Test (SNOT-5) to evaluate disease severity and to compare its results with objective assessments in patients with CRSwNP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adult patients with bilateral CRSwNP planning to undergo sinus surgery were prospectively enrolled. The nasal polyp score (NPS), Lund-Mackay (L-M) score, olfactory cleft opacification (OC) score, and the 22-item Sino-Nasal Outcome Test (SNOT-22) questionnaire were assessed. The SNOT-5 scores were retrospectively extracted from the SNOT-22 results. Three-month postoperative endoscopic modified Lund-Kennedy (MLK) scores and SNOT-22 data were collected when available.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 169 participants were enrolled. The SNOT-5 score rather than the SNOT-22 score, was significantly correlated with objective measurements of disease burden, including NPS, L-M, and OC scores. SNOT-5 score was significantly associated with younger age, comorbid asthma, NPS, L-M, and OC scores in the univariate regression analysis, and with age, L-M, and OC scores in the multivariate analysis. Additionally, the SNOT-5 score also significantly correlated with the MLK score at 3 months after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The SNOT-5, rather than the SNOT-22, correlated more closely with objective measures of disease burden, including the NPS and L-M scores, and postoperative MLK score in patients with CRSwNP. Utilizing the SNOT-5 in clinical practice may help clinicians more accurately assess disease severity and treatment response in patients with CRSwNP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19458924251399711","type":"journal-article","created":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T14:43:08Z","timestamp":1764772988000},"page":"160-168","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Five-item Sino-Nasal Outcome Test in Evaluation of Disease Burden in Chronic Rhinosinusitis With Nasal Polyps"],"prefix":"10.1177","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7549-9633","authenticated-orcid":false,"given":"Pei-Wen","family":"Wu","sequence":"first","affiliation":[{"name":"Chang Gung Memorial Hospital and Chang Gung University"},{"name":"School of Medicine, Chang Gung University, Taoyuan, Taiwan"},{"name":"Chang Gung Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Che","family":"Huang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital and Chang Gung University"},{"name":"School of Medicine, Chang Gung University, Taoyuan, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Hung","family":"Chang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital and Chang Gung University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ta-Jen","family":"Lee","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital and Chang Gung University"},{"name":"School of Medicine, Chang Gung University, Taoyuan, Taiwan"},{"name":"Department of Otolaryngology, Xiamen Chang Gung Hospital, Xiamen, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4188-3498","authenticated-orcid":false,"given":"Chien-Chia","family":"Huang","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital and Chang Gung University"},{"name":"School of Medicine, Chang Gung University, Taoyuan, Taiwan"},{"name":"Chang Gung Memorial Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,3]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"1","article-title":"European position paper on rhinosinusitis and nasal polyps 2020","volume":"58","author":"Fokkens WJ","year":"2020","unstructured":"Fokkens WJ, Lund VJ, Hopkins C, et al. European position paper on rhinosinusitis and nasal polyps 2020. Rhinology. 2020;58(Suppl S29):1-464.","journal-title":"Rhinology"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22741"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/all.15650"},{"key":"e_1_3_2_5_2","article-title":"Staging for rhinosinusitis","volume":"117","author":"Lund VJ","year":"1997","unstructured":"Lund VJ, Kennedy DW. Staging for rhinosinusitis. Otolaryngol Head Neck Surg. 1997;117(3 Pt 2):S35-S40.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.31899"},{"issue":"3","key":"e_1_3_2_7_2","first-page":"348","article-title":"Tissue eosinophilia and computed tomography features in paediatric chronic rhinosinusitis with nasal polyps requiring revision surgery","volume":"61","author":"Wu PW","year":"2023","unstructured":"Wu PW, Chiu CH, Huang YL, et al. Tissue eosinophilia and computed tomography features in paediatric chronic rhinosinusitis with nasal polyps requiring revision surgery. 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Correlation of polyp grading scales with patient symptom scores and olfaction in chronic rhinosinusitis: A systematic review and meta-analysis. 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