{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T02:44:59Z","timestamp":1786243499462,"version":"build-2736575974"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>No prior national-level hospital admission analysis has compared acute rhinosinusitis (ARS) outcomes between cystic fibrosis (CF) and non-CF pediatric patients, leaving clinicians without population-level data to contextualize hospitalization burden and complication rates in this group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We aimed to compare the complication risks and healthcare utilization between patients with CF versus without CF in children hospitalized with ARS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study examined inpatient admissions for pediatric ARS patients with or without CF in 2003-2019 using the Kids\u2019 Inpatient Database (KID), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality. Outcomes included orbital complications, intracranial complications, sinus involvement, sinus procedure rates, length of stay, and hospital charges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the weighted 41,148 patients with ARS, 1.5% had CF (n\u2009=\u2009632). CF patients had lower odds of orbital complications (aOR 0.09, 95% CI 0.04-0.20,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) but higher odds of sinus procedures (aOR 1.59, 95% CI 1.14-2.20,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.006) compared to non-CF patients. CF patients also had longer hospital stays (8 vs 3 days,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) and higher hospital charges ($43,918 vs $11,129,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001) compared to non-CF patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Children with concurrent CF and ARS experience greater overall disease burden, reflected in prolonged hospitalization, higher healthcare costs, and higher rates of sinus surgeries. However, CF patients appear less prone to orbital complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19458924261473981","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T15:28:52Z","timestamp":1785943732000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Complicated Acute Rhinosinusitis in Cystic Fibrosis: National Inpatient Pediatric Analysis"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9731-9429","authenticated-orcid":false,"given":"Emily S.","family":"Kwon","sequence":"first","affiliation":[{"name":"Rutgers Health New Jersey Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saharsh","family":"Talwar","sequence":"additional","affiliation":[{"name":"Rutgers Robert Wood Johnson Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5276-860X","authenticated-orcid":false,"given":"Annie","family":"Xu","sequence":"additional","affiliation":[{"name":"Rutgers Health New Jersey Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudeepti","family":"Vedula","sequence":"additional","affiliation":[{"name":"Rutgers Health New Jersey Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Kaye","sequence":"additional","affiliation":[{"name":"Rutgers Health New Jersey Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyne","family":"Kalyoussef","sequence":"additional","affiliation":[{"name":"Rutgers Health New Jersey Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne Daniel","family":"Hsueh","sequence":"additional","affiliation":[{"name":"Rutgers Health New Jersey Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,5]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348941212100904"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.578"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.01.020"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599818815109"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1542\/pir.2019-0212"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2013.27.3919"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2017.08.022"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23046"},{"key":"e_1_3_2_10_2","unstructured":"Healthcare Cost and Utilization Project (HCUP). 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