{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T04:10:47Z","timestamp":1792210247654,"version":"4.4.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2015,7,22]],"date-time":"2015-07-22T00:00:00Z","timestamp":1437523200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["CARTILAGE"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To assess the outcome of osteochondral allograft (OCA) transplantation as the primary treatment for cartilage injury in patients with no previous surgical treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Case series. Patients were identified in our outcomes database. Patients undergoing primary OCA transplantation with no prior surgical treatment and a minimum of 2 years follow-up were selected. Pain and function were evaluated preoperatively and postoperatively. Patient satisfaction was assessed. Reoperations following OCA transplantation were captured. Failure was defined as revision OCA or conversion to arthroplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifty-five patients (61 knees) were included in the analysis. The study consisted of 30 males and 25 females (mean age = 32.9 years; range = 15.7-67.8 years). The most common diagnoses for the OCA transplantation were osteochondritis dissecans (44.3%) and avascular necrosis (31.1%). Pain and function improved preoperatively to postoperatively on all outcome scales ( P &lt; 0.01). The majority of patients (86%) were \u201cextremely satisfied\u201d or \u201csatisfied.\u201d OCA survivorship was 89.5% at 5 years and 74.7% at 10 years. At latest follow-up (mean = 7.6 years; range = 1.9-22.6 years), OCA remained in situ in 50 knees (82%). Eighteen knees (29.5%) had further surgery; 11 OCA failures and 7 other surgical procedure(s). Of the failed knees (mean time to failure = 3.5 years; range = 0.5-13.7 years), 8 were converted to arthroplasty, 2 had OCA revisions, and 1 had a patellectomy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>OCA transplantation is an acceptable primary treatment method for some chondral and osteochondral defects of the knee. Failure of previous treatment(s) is not a prerequisite for OCA transplantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1947603515595072","type":"journal-article","created":{"date-parts":[[2015,7,22]],"date-time":"2015-07-22T20:49:06Z","timestamp":1437598146000},"page":"203-207","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":79,"title":["The Use of Osteochondral Allograft Transplantation for Primary Treatment of Cartilage Lesions in the Knee"],"prefix":"10.1177","volume":"6","author":[{"given":"Dustin T.","family":"Briggs","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, University of New Mexico, Albuquerque, NM, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran N.","family":"Sadr","sequence":"additional","affiliation":[{"name":"Kaiser Permanente, Freemont, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela A.","family":"Pulido","sequence":"additional","affiliation":[{"name":"Shiley Center for Orthopaedic Research & Education at Scripps Clinic, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William D.","family":"Bugbee","sequence":"additional","affiliation":[{"name":"Shiley Center for Orthopaedic Research & Education at Scripps Clinic, La Jolla, CA, USA"},{"name":"Division of Orthopaedics, Scripps Clinic, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,7,22]]},"reference":[{"key":"bibr1-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1177\/0363546505274578"},{"key":"bibr2-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508328414"},{"key":"bibr3-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2003.50112"},{"key":"bibr4-1947603515595072","doi-asserted-by":"crossref","unstructured":"Gudas R, Gudaite A, Pocius A, Gudiene A, Cekanauskas E, Monastyreckiene E, Ten-year follow-up of a prospective, randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint of athletes. Am J Sports Med. 2012;40:2499-508.","DOI":"10.1177\/0363546512458763"},{"key":"bibr5-1947603515595072","first-page":"191","volume":"15","author":"Bugbee WD","year":"2002","journal-title":"J Knee Surg"},{"key":"bibr6-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507299932"},{"key":"bibr7-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.79B6.0791008"},{"key":"bibr8-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-010-1250-7"},{"key":"bibr9-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0282-8"},{"key":"bibr10-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000165845.21735.05"},{"key":"bibr11-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000165854.15579.85"},{"key":"bibr12-1947603515595072","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.H.00703"},{"key":"bibr13-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-012-2556-4"},{"key":"bibr14-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-012-2523-0"},{"key":"bibr15-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000201152.98830.ed"},{"key":"bibr16-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-191408000-00005"},{"key":"bibr17-1947603515595072","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200606000-00030"},{"key":"bibr18-1947603515595072","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509331419"},{"key":"bibr19-1947603515595072","doi-asserted-by":"crossref","unstructured":"Knutsen G, Drogset JO, Engebretsen L, Grontvedt T, Isaksen V, Ludvigsen TC, A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years. 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