{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:55:49Z","timestamp":1777478149620,"version":"3.51.4"},"reference-count":28,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T00:00:00Z","timestamp":1538524800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703896"],"award-info":[{"award-number":["81703896"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"the Capital Health Research and Development of Special","doi-asserted-by":"crossref","award":["2016-2-4062"],"award-info":[{"award-number":["2016-2-4062"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100009592","name":"Beijing municipal science and technology commission","doi-asserted-by":"crossref","award":["Z171100001017209"],"award-info":[{"award-number":["Z171100001017209"]}],"id":[{"id":"10.13039\/501100009592","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["CARTILAGE"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Hip cartilage quality is essential for the success of joint-preserving surgery for osteonecrosis. This study aimed to characterize cartilage changes in osteonecrosis of femoral head (ONFH) using delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Fifteen asymptomatic (control) and 60 ONFH subjects were included in this study. The ONFH subjects were stratified in accordance with the Association Research Circulation Osseous (ARCO) classification ( n = 15 hips per ARCO stage). All participant hips were investigated using dGEMRIC and theT1Gd data were collected and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>T1Gd value was significantly lower in the ONFH group (365.1 \u00b1 90.5 ms; range 200-498 ms) compared with the control group (546.1 \u00b1 26.0 ms; range 504-580 ms) ( P &lt; 0.001). The T1Gd values of ARCO stage I-IV ONFH were 460.2 \u00b1 17.3 ms (439-498 ms), 408.9 \u00b1 43.4 ms (337-472 ms), 359.9 \u00b1 34.5 ms (303-412 ms), 231.5 \u00b1 15.1 ms (200-253 ms), respectively. Decreased T1Gd value was found to correlate significantly with increased ONFH severity ( P &lt; 0.001). T1Gd value in collapse stage was significantly lower than that of noncollapse stage (295.7 \u00b1 70.3 ms [range 200-412 ms] vs. 434.6 \u00b1 41.7 ms [range 337-498 ms]; P &lt; 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>dGEMRIC identified hip cartilage as abnormal in ONFH, even at early-stage, as represented by decreased T1Gd, and this was further aggravated by ONFH collapse.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1947603518803732","type":"journal-article","created":{"date-parts":[[2018,10,4]],"date-time":"2018-10-04T02:03:31Z","timestamp":1538618611000},"page":"70-75","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The Glycosaminoglycan Content of Hip Cartilage in Osteonecrosis of Femoral Head: Evaluation with Delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Cartilage"],"prefix":"10.1177","volume":"12","author":[{"given":"Qidong","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Beijing Key Lab Immune-Mediated Inflammatory Diseases, China-Japan Friendship Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanshou","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Beijing Key Lab Immune-Mediated Inflammatory Diseases, China-Japan Friendship Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology, China-Japan Friendship Hospital, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qichao","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Radiology, China-Japan Friendship Hospital, Beijing, 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