{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T15:56:21Z","timestamp":1777478181984,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"1_suppl","license":[{"start":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T00:00:00Z","timestamp":1562803200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["CARTILAGE"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Accurate, high-resolution imaging of articular cartilage thickness is an important clinical challenge in patients with osteoarthritis, especially in small joints. In this study, computed tomography (CT) mediated catheter-based optical coherence tomography (OCT) was utilized to create a digital reconstruction of the articular surface of the trapeziometacarpal (TMC) joint and to assess cartilage thickness in comparison to cryomicrotome data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Using needle-based introduction of the OCT probe, the articular surface of the TMC joint of 5 cadaver wrists was scanned in different probe positions with matching CT scans to record the intraarticular probe trajectory. Subsequently and based on the acquired CT data, 3-dimensional realignment of the OCT data to the curved intraarticular trajectory was performed for all probe positions. The scanned TMC joints were processed using a cryomicrotome imaging system. Finally, cartilage thickness measurements between OCT and cryomicrotome data were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Successful visualization of TMC articular cartilage was performed using OCT. The CT-mediated registration yielded a digital reconstruction of the articular surface on which thickness measurements could be performed. A near-perfect agreement between OCT and cryomicrotome thickness measurements was found ( r\n                      <jats:sup>2<\/jats:sup>\n                      = 0.989).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The proposed approach enables 3D reconstruction of the TMC articular surface with subsequent accurate cartilage thickness measurements, encouraging the development of intraarticular cartilage OCT for future (clinical) application.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1947603519860247","type":"journal-article","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T03:04:26Z","timestamp":1562814266000},"page":"563S-570S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Computed Tomography\u2013Mediated Registration of Trapeziometacarpal Articular Cartilage Using Intraarticular Optical Coherence Tomography and Cryomicrotome Imaging: A Cadaver Study"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3483-513X","authenticated-orcid":false,"given":"Paul","family":"Cernohorsky","sequence":"first","affiliation":[{"name":"Plastic, Reconstructive and Hand Surgery, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon D.","family":"Strackee","sequence":"additional","affiliation":[{"name":"Plastic, Reconstructive and Hand Surgery, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geert J.","family":"Streekstra","sequence":"additional","affiliation":[{"name":"Biomedical Engineering and Physics, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"},{"name":"Radiology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeroen P.","family":"van den Wijngaard","sequence":"additional","affiliation":[{"name":"Biomedical Engineering and Physics, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos A. E.","family":"Spaan","sequence":"additional","affiliation":[{"name":"Biomedical Engineering and Physics, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7034-5843","authenticated-orcid":false,"given":"Maria","family":"Siebes","sequence":"additional","affiliation":[{"name":"Biomedical Engineering and Physics, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ton G.","family":"van Leeuwen","sequence":"additional","affiliation":[{"name":"Biomedical Engineering and Physics, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel M.","family":"de Bruin","sequence":"additional","affiliation":[{"name":"Biomedical Engineering and Physics, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"},{"name":"Urology, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,7,11]]},"reference":[{"key":"bibr1-1947603519860247","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.023564"},{"key":"bibr2-1947603519860247","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.104562"},{"key":"bibr3-1947603519860247","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60243-2"},{"key":"bibr4-1947603519860247","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0712(21)00761-7"},{"key":"bibr5-1947603519860247","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2011.06.017"},{"key":"bibr6-1947603519860247","doi-asserted-by":"publisher","DOI":"10.1053\/jhsu.1999.0777"},{"issue":"5","key":"bibr7-1947603519860247","volume":"182","author":"Haims AH","year":"2004","journal-title":"et 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