{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:20:14Z","timestamp":1793092814679,"version":"4.5.0"},"reference-count":46,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["CARTILAGE"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine and compare the incidence rate of (osteo)chondral lesions of the ankle in patients with acute and chronic isolated syndesmotic injuries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A literature search was conducted in the PubMed (MEDLINE) and EMBASE (Ovid) databases from 2000 to September 2021. Two authors independently screened the search results, and risk of bias was assessed using the MINORS (Methodological Index for Non-Randomized Studies) criteria. Studies on acute and chronic isolated syndesmotic injuries with pre-operative or intra-operative imaging were included. The primary outcome was the incidence rate with corresponding 95% confidence intervals (CIs) of (osteo)chondral lesions of the ankle in combined and separate groups of acute and chronic syndesmotic injuries. Secondary outcomes were anatomic distribution and mean size of the (osteo)chondral lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nine articles (402 syndesmotic injuries) were included in the final analysis. Overall (osteo)chondral lesion incidence was 20.7% (95% CI: 13.7%-29.9%). This rate was 22.0% (95% CI: 17.1-27.7) and 24.1% (95% CI: 15.6-35.2) for acute and chronic syndesmotic injuries, respectively. In the combined acute and chronic syndesmotic injury group, 95.4% of the lesions were located on the talar dome and 4.5% of the lesions were located on the distal tibia. (Osteo)chondral lesion size was not reported in any of the studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This meta-analysis shows that (osteo)chondral lesions of the ankle are present in 21% of the patients with isolated syndesmotic injuries. No difference in incidence rate was found between the different syndesmotic injury types and it can be concluded that the majority of lesions are located on the talar dome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO Registration Number:<\/jats:title>\n                    <jats:p>CRD42020176641<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19476035221102569","type":"journal-article","created":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T09:54:37Z","timestamp":1654250077000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Incidence of (Osteo)Chondral Lesions of the Ankle in Isolated Syndesmotic Injuries: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6849-1008","authenticated-orcid":false,"given":"Jari","family":"Dahmen","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Academic Center for Evidence-Based Sports Medicine, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Amsterdam Collaboration for Health and Safety in Sports, International Olympic Committee Research Center, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Foot &amp; Ankle Research and Innovation Lab, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA"},{"name":"Department of Orthopaedic Surgery, Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar"},{"name":"Department of Orthopaedic Surgery, NYU Langone Health, New York, NY, USA"},{"name":"Fortius Clinic, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sohaib","family":"Jaddi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Academic Center for Evidence-Based Sports Medicine, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Amsterdam Collaboration for Health and Safety in Sports, International Olympic Committee Research Center, Amsterdam UMC, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noortje C.","family":"Hagemeijer","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Academic Center for Evidence-Based Sports Medicine, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Amsterdam Collaboration for Health and Safety in Sports, International Olympic Committee Research Center, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Foot &amp; Ankle Research and Innovation Lab, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart","family":"Lubberts","sequence":"additional","affiliation":[{"name":"Foot &amp; Ankle Research and Innovation Lab, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger N.","family":"Sierevelt","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Academic Center for Evidence-Based Sports Medicine, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Amsterdam Collaboration for Health and Safety in Sports, International Olympic Committee Research Center, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Department of Orthopaedic Surgery, Xpert Clinics, Specialized Center of Orthopaedic Research and Education, Amsterdam, The Netherlands"},{"name":"Department of Orthopedic Surgery, Spaarne Gasthuis Academy, Hoofddorp, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sjoerd A.S.","family":"Stufkens","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Academic Center for Evidence-Based Sports Medicine, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Amsterdam Collaboration for Health and Safety in Sports, International Olympic Committee Research Center, Amsterdam UMC, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter","family":"d\u2019Hooghe","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, NYU Langone Health, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D. F.","family":"Calder","sequence":"additional","affiliation":[{"name":"Fortius Clinic, London, UK"},{"name":"Department of Bioengineering, Imperial College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher W.","family":"DiGiovanni","sequence":"additional","affiliation":[{"name":"Massachusetts General Hospital, Newton-Wellesley Hospital and Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gino M. M. J.","family":"Kerkhoffs","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, Amsterdam Movement Sciences, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Academic Center for Evidence-Based Sports Medicine, Amsterdam UMC, Amsterdam, The Netherlands"},{"name":"Amsterdam Collaboration for Health and Safety in Sports, International Olympic Committee Research Center, Amsterdam UMC, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,3]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199506000-00005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/17453670610012557"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-06187-y"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-100298"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-06141-y"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-017-9389-4"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/1947603520954510."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2011.03242.x"},{"key":"e_1_3_3_11_2","article-title":"Classification and diagnosis of acute isolated syndesmotic injuries: ESSKA-AFAS consensus and guidelines","volume":"24","author":"van Dijk CN","year":"2016","unstructured":"van Dijk CN, Longo UG, Loppini M, Florio P, Maltese L, Ciuffreda M, et al. Classification and diagnosis of acute isolated syndesmotic injuries: ESSKA-AFAS consensus and guidelines. Knee Surg Sports Traumatol Arthrosc. 2016;24:1200-16.","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02748.x"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2015.06.009"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2017-097710"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fcl.2006.07.006"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20121120-13"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/107110070002100805"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.12"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.3113\/FAI.2007.0154"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v036.i03"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.3113\/FAI.2007.0336"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-05962-1"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1177\/2325967119871578"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514529643"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.3113\/FAI.2012.0371"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546504270566"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.fas.2008.04.002"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.3113\/FAI.2009.0524"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198668060-00007"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354658901700223"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1950.01250010980011"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-016-4043-z"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2017-098106"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1177\/1947603519876353"},{"key":"e_1_3_3_36_2","article-title":"The ankle syndesmosis pivot shift \u201cAre we reviving the ACL story?","volume":"29","author":"Tampere T","year":"2021","unstructured":"Tampere T, D\u2019Hooghe P. The ankle syndesmosis pivot shift \u201cAre we reviving the ACL story? \u201d Knee Surg Sports Traumatol Arthrosc. 2021;29:3508-11.","journal-title":"\u201d Knee Surg Sports Traumatol Arthrosc"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-11-75"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1177\/2325967120922821"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.G.00087"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2010.05.013"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197658030-00010"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2006.2195"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1177\/1071100720929007"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-06308-7"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2015.10.003"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-05889-7"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-020-05898-6"}],"container-title":["CARTILAGE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19476035221102569","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19476035221102569","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19476035221102569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T13:58:54Z","timestamp":1777384734000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19476035221102569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1177\/19476035221102569"],"URL":"https:\/\/doi.org\/10.1177\/19476035221102569","relation":{},"ISSN":["1947-6035","1947-6043"],"issn-type":[{"value":"1947-6035","type":"print"},{"value":"1947-6043","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4]]},"article-number":"19476035221102569"}}