{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T07:12:12Z","timestamp":1787987532284,"version":"build-2784847793"},"reference-count":7,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T00:00:00Z","timestamp":1456358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neuroradiol J"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:p>Krabbe\u2019s disease (KD) and metachromatic leucodystrophy (MLD) are both lysosomal storage disorders that share some common MRI features. Amongst the imaging findings useful to distinguish one from the other, optic chiasm\/nerves thickening have been described as specific key features for differential diagnosis favouring KD. We report the first case of enlargement of the optic nerves and chiasm described in a patient with genetically confirmed MLD.<\/jats:p>","DOI":"10.1177\/1971400916633479","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T21:59:33Z","timestamp":1456437573000},"page":"134-136","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Thickening of the optic nerves in metachromatic leucodystrophy: A new MRI finding"],"prefix":"10.1177","volume":"29","author":[{"given":"Dylan","family":"Roi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kshitij","family":"Mankad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marios","family":"Kaliakatsos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Cleary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Manzur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felice","family":"D\u2019Arco","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,2,25]]},"reference":[{"key":"bibr1-1971400916633479","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.22.3.g02ma01461"},{"key":"bibr2-1971400916633479","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1249654"},{"key":"bibr3-1971400916633479","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139030854.035"},{"key":"bibr4-1971400916633479","doi-asserted-by":"crossref","unstructured":"Kohlsch\u00fctter A. Lysosomal leukodystrophies: Krabbe disease and metachromatic leukodystrophy. In: Dulac O, Lassonde M, Sartnat HB (eds)\n                      Handbook of Clinical Neurology\n                      . Vol 113 (3rd series) Pediatric Neurology Part III. Amsterdam: Elsevier, 2013.","DOI":"10.1016\/B978-0-444-59565-2.00029-0"},{"key":"bibr5-1971400916633479","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1739"},{"key":"bibr6-1971400916633479","first-page":"1228","volume":"20","author":"Jones BV","year":"1999","journal-title":"AJNR Am J Neuroradiol"},{"key":"bibr7-1971400916633479","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1979.01020020157015"}],"container-title":["The Neuroradiology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1971400916633479","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1971400916633479","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1971400916633479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:32:49Z","timestamp":1777588369000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1971400916633479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,25]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1177\/1971400916633479"],"URL":"https:\/\/doi.org\/10.1177\/1971400916633479","relation":{},"ISSN":["1971-4009","2385-1996"],"issn-type":[{"value":"1971-4009","type":"print"},{"value":"2385-1996","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,25]]}}}