{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:16:03Z","timestamp":1787019363075,"version":"build-2736575974"},"reference-count":30,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T00:00:00Z","timestamp":1600041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neuroradiol J"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background and purpose<\/jats:title>\n                    <jats:p>In the 2016 revision of the World Health Organization classification of central nervous system tumours, brain invasion was added as an independent histological criterion for the diagnosis of a World Health Organization grade II atypical meningioma. The aim of this study was to assess whether magnetic resonance imaging characteristics can predict brain invasion for meningiomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>We conducted a retrospective review of all meningiomas resected at our institution between 2005 and 2016 which had preoperative magnetic resonance imaging and included brain tissue within the pathology specimen. One hundred meningiomas were included in the study, 60 of which had histopathological brain invasion, 40 of which did not. Magnetic resonance imaging characteristics of tumours were evaluated for potential predictors of brain invasion. Tumour location, size, perilesional oedema, contour, cerebrospinal fluid cleft, peritumoral cyst, dural venous sinus invasion, bone invasion, hyperostosis and the presence of enlarged pial arteries and veins were evaluated. Data were analysed using conventional chi-square, Fisher\u2019s exact test and logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The volume of peritumoral oedema was significantly higher in the brain-invasive meningioma group compared to the non-brain-invasive group. The presence of a complete cleft was a rare finding that was only found in non-brain-invasive meningiomas. The presence of enlarged pial feeding arteries was a rare finding that was only found in brain-invasive meningiomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>An increased volume of perilesional oedema is associated with the likelihood of brain invasion for meningiomas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1971400920953417","type":"journal-article","created":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T07:35:59Z","timestamp":1600068959000},"page":"3-7","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":22,"title":["MRI predictors for brain invasion in meningiomas"],"prefix":"10.1177","volume":"34","author":[{"given":"Thomas","family":"Ong","sequence":"first","affiliation":[{"name":"Division of Neuroradiology, St Michael\u2019s Hospital, Toronto, Canada"},{"name":"Department of Medical Imaging, University of Toronto, Canada"},{"name":"Department of Radiology, Jewish General Hospital, Montreal, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7923-7865","authenticated-orcid":false,"given":"Aditya","family":"Bharatha","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, St Michael\u2019s Hospital, Toronto, Canada"},{"name":"Department of Medical Imaging, University of Toronto, Canada"},{"name":"Division of Neurosurgery, St Michael\u2019s Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8243-5136","authenticated-orcid":false,"given":"Reema","family":"Alsufayan","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, St Michael\u2019s Hospital, Toronto, Canada"},{"name":"Department of Medical Imaging, University of Toronto, Canada"},{"name":"Johns Hopkins Aramco Healthcare, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunit","family":"Das","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, St Michael\u2019s Hospital, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2505-7340","authenticated-orcid":false,"given":"Amy Wei","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, St Michael\u2019s Hospital, Toronto, Canada"},{"name":"Department of Medical Imaging, University of Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,9,14]]},"reference":[{"key":"bibr1-1971400920953417","author":"Watts J","journal-title":"Insights Imaging"},{"key":"bibr2-1971400920953417","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2010.11.008"},{"key":"bibr3-1971400920953417","author":"Johnson DR","journal-title":"RadioGraphics"},{"key":"bibr4-1971400920953417","author":"Brokinkel B","journal-title":"Neuro Oncol"},{"key":"bibr5-1971400920953417","author":"Toh CH","journal-title":"Am J Neuroradiol"},{"key":"bibr6-1971400920953417","author":"Hou W","journal-title":"Oncol Lett"},{"key":"bibr7-1971400920953417","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.26313"},{"key":"bibr8-1971400920953417","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.91.3.0375"},{"key":"bibr9-1971400920953417","author":"Louis DN","journal-title":"Acta Neuropathol"},{"key":"bibr10-1971400920953417","author":"Perry A","journal-title":"Am J Surg Pathol"},{"key":"bibr11-1971400920953417","author":"Hale AT","journal-title":"J Clin Neurosci"},{"key":"bibr12-1971400920953417","author":"Lee KJ","journal-title":"Surg Neurol"},{"key":"bibr13-1971400920953417","author":"Hakyemez B","journal-title":"Neuroradiology"},{"key":"bibr14-1971400920953417","author":"Surov A","journal-title":". 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