{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T08:55:13Z","timestamp":1782377713884,"version":"3.54.5"},"reference-count":32,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neuroradiol J"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The aetiologic diagnosis of non-traumatic acute myelopathies (AMs), and their differentiation from other mimicking conditions (i.e. \u2018mimics\u2019), are clinically challenging, especially in the emergency setting. Here, we sought to identify: (i) red flags suggesting diagnoses alternative to AMs and (ii) clinical signs and magnetic resonance imaging (MRI) features differentiating non-compressive from compressive AMs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>We retrospectively retrieved MRI scans of spinal cord dictated at emergency room from January 2016 to December 2020 in the suspicion of AMs. Patients with traumatic myelopathies and those with subacute\/chronic myelopathies (i.e. MRI scans acquired &gt;48 h from symptom onset) were excluded from analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Our search retrieved 105 patients; after excluding 16 cases of traumatic myelopathies and 14 cases of subacute\/chronic myelopathies, we identified 30 cases with non-compressive AMs, 30 cases with compressive AMs and 15 mimics. The presence of pyramidal signs ( p = 0.012) and\/or pain ( p = 0.048) correctly identified 88% of cases with AMs. We failed to identify clinical indicators for distinguishing non-compressive and compressive AMs, although cases with inflammatory AMs were younger than cases with all the remaining conditions ( p &lt; 0.05). Different MRI patterns could be described according to the final diagnosis: among non-compressive AMs, inflammatory lesions were more often posterior or central; vascular malformation had a fairly widespread distribution; spine ischaemia was more often central. Anterior or lateral compression were more often associated with neoplasms and disc herniation , whereas hemorrhages and infections produced spine compression on all sides.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We propose a simple clinical indicator (i.e. pyramidal signs and\/or pain) to distinguish AMs from their mimics in an emergency setting. Urgent spinal cord MRI remains essential to discriminate compressive and non-compressive aetiologies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19714009221096823","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T18:36:36Z","timestamp":1652898996000},"page":"727-735","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Non-traumatic acute myelopathies: Clinical and imaging features in a real world emergency setting"],"prefix":"10.1177","volume":"35","author":[{"given":"Alessandro","family":"Stasolla","sequence":"first","affiliation":[{"name":"Neuroradiology Unit, S. Camillo-Forlanini Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3237-6267","authenticated-orcid":false,"given":"Luca","family":"Prosperini","sequence":"additional","affiliation":[{"name":"Neurology Unit, S. Camillo-Forlanini Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalom","family":"Haggiag","sequence":"additional","affiliation":[{"name":"Neurology Unit, S. Camillo-Forlanini Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca R","family":"Pezzella","sequence":"additional","affiliation":[{"name":"Stroke Unit, S. Camillo-Forlanini Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Pingi","sequence":"additional","affiliation":[{"name":"Neuroradiology Unit, S. Camillo-Forlanini Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Cozzolino","sequence":"additional","affiliation":[{"name":"Neuroradiology Unit, S. Camillo-Forlanini Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Pampana","sequence":"additional","affiliation":[{"name":"Neuroradiology Unit, S. 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