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Carcinoma of an unknown primary site (CUP) metastasizing into an intracranial meningioma is not a common occasion. According to the best of our knowledge, in this report, we present the first case with multiple recurrent CUP, which metastasized to intracranial meningioma, reported in the literature. The whole body was investigated with FDG PET\/CT and biomarkers of the most common carcinomas for primary cancer. However, these tests showed no primary affected region. Despite all adjuvant therapies, the tumor had multiple recurrences. Such cases are still a challenge to offer optimal management.<\/jats:p>","DOI":"10.1177\/19714009221096836","type":"journal-article","created":{"date-parts":[[2022,4,29]],"date-time":"2022-04-29T23:51:30Z","timestamp":1651276290000},"page":"763-767","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Multiple recurrences of unknown primary tumor in a meningioma: A case report"],"prefix":"10.1177","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8325-2382","authenticated-orcid":false,"given":"Muhammed Amir","family":"Essibayi","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Bezmialem Vakif University, Istanbul, Turkey"},{"name":"Equal contribution."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anas","family":"Abdallah","sequence":"additional","affiliation":[{"name":"Osmaniye State Hospital, D400 Karayolu \u00dczeri Akyar Mevkii, Osmaniye"},{"name":"Equal contribution."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erdin\u00e7","family":"\u00d6zek","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Bezmialem Vakif University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ganime","family":"Coban","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bezmialem Vakif University, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,4,29]]},"reference":[{"key":"bibr1-19714009221096836","doi-asserted-by":"publisher","DOI":"10.14791\/btrt.2016.4.2.107"},{"key":"bibr2-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2008.07.011"},{"key":"bibr3-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-007-1239-5"},{"key":"bibr4-19714009221096836","first-page":"350","volume":"104","author":"Chambers PW","year":"1980","journal-title":"Arch Pathol Lab Med"},{"key":"bibr5-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19811215)48:12<2668::AID-CNCR2820481219>3.0.CO;2-N"},{"issue":"2","key":"bibr6-19714009221096836","first-page":"151","volume":"24","author":"Erdogan H","year":"2014","journal-title":"Turkish Neurosurg"},{"key":"bibr7-19714009221096836","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.579599"},{"issue":"3","key":"bibr8-19714009221096836","first-page":"323","volume":"30","author":"Abdallah A","year":"2020","journal-title":"Turkish Neurosurg"},{"key":"bibr9-19714009221096836","doi-asserted-by":"publisher","DOI":"10.2217\/cns-2017-0022"},{"key":"bibr10-19714009221096836","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.5655"},{"key":"bibr11-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-019-1596-6"},{"key":"bibr12-19714009221096836","first-page":"816","volume":"41","author":"Bohuslavizki KH","year":"2000","journal-title":"J Nucl Med"},{"key":"bibr13-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-009-1295-6"},{"key":"bibr14-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006713"},{"issue":"1","key":"bibr15-19714009221096836","first-page":"75","volume":"35","author":"Abdallah A","year":"2021","journal-title":"Rom Neurosurg"},{"key":"bibr16-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/59.12.1044"},{"key":"bibr17-19714009221096836","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-020-04661-7"}],"container-title":["The Neuroradiology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19714009221096836","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19714009221096836","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19714009221096836","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:37:04Z","timestamp":1777588624000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19714009221096836"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,29]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1177\/19714009221096836"],"URL":"https:\/\/doi.org\/10.1177\/19714009221096836","relation":{},"ISSN":["1971-4009","2385-1996"],"issn-type":[{"value":"1971-4009","type":"print"},{"value":"2385-1996","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,29]]}}}