{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T05:56:21Z","timestamp":1792475781766,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T00:00:00Z","timestamp":1655164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neuroradiol J"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The optimal management of patients with acute ischemic stroke (AIS) due to tandem occlusion (TO) and underlying carotid dissection (CD) remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>We present our multicenter-experience of endovascular treatment (EVT) approach used and outcomes for AIS patients with CD-related TO (CD-TO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Consecutive AIS patients underwent EVT for CD-TO at five Italian Neuro-interventional Tertiary Stroke Centers were retrospectively identified. TO from atherosclerosis and other causes of, were excluded from the final analysis. Primary outcome was successful (mTICI 2b-3) and complete reperfusion (mTICI 3); secondary outcome was patients\u2019 3-months functional independence (mRS\u22642).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 214 AIS patients with TO, 45 presented CD-TO. Median age was 54 years (range 29\u201386), 82.2% were male. Age &lt;65 years ( p &lt; 0.0001), lower baseline NIHSS score ( p = 0.0002), and complete circle of Willis ( p = 0.0422) were associated with mRS \u2264 2 at the multivariate analysis. Comparisons between antegrade and retrograde approaches resulted in differences for baseline NIHSS scores ( p = 0.001) and number of EVT attempts per-procedure ( p = 0.001). No differences in terms of recanalization rates were observed between antegrade and retrograde EVT approaches ( p = 0.811) but higher rates of mTICI3 revascularization was observed with the retrograde compared to the antegrade approach (78.6% vs 73.3%), anyway not statistically significant. CD management technique (angioplasty vs aspiration vs emergent stenting) did not correlate with 3-months mRS\u22642.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>AIS patients with CD-TO were mostly treated with the retrograde approach with lower number of attempts per-procedure but it offered similar recanalization rates compared with the antegrade approach. Emergent carotid artery stenting (CAS) proved to be safe for CD management but it does not influence 3-months patients\u2019 clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19714009221108673","type":"journal-article","created":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T06:41:08Z","timestamp":1655188868000},"page":"86-93","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Endovascular treatment of patients with acute ischemic stroke and tandem occlusion due to internal carotid artery dissection: A multicenter experience"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7167-7594","authenticated-orcid":false,"given":"Valerio","family":"Da Ros","sequence":"first","affiliation":[{"name":"Diagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8388-0178","authenticated-orcid":false,"given":"Federica","family":"Pusceddu","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Lattanzi","sequence":"additional","affiliation":[{"name":"Neurological Clinic, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9531-9131","authenticated-orcid":false,"given":"Jacopo","family":"Scaggiante","sequence":"additional","affiliation":[{"name":"Department of Radiology and Radiological Science, Medical University of South Carolina, Charleston, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Sallustio","sequence":"additional","affiliation":[{"name":"Comprehensive Stroke Center, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Marrama","sequence":"additional","affiliation":[{"name":"Comprehensive Stroke Center, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Bandettini di Poggio","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Policlinico Hospital San Martino, University of Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianpaolo","family":"Toscano","sequence":"additional","affiliation":[{"name":"Stroke Unit University Policlinico San Matteo, IRCCS Mondino Fundation, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Di Giuliano","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Rolla-Bigliani","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, University Hospital, San Martino, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Ruggiero","sequence":"additional","affiliation":[{"name":"Neuroradiology Unit, AUSL Romagna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niccolo","family":"Haznedari","sequence":"additional","affiliation":[{"name":"Neuroradiology Unit, AUSL Romagna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0834-644X","authenticated-orcid":false,"given":"Alessandro","family":"Sgreccia","sequence":"additional","affiliation":[{"name":"Clinic of Neuroradiology and Interventional Neuroradiology, AOU Ospedali Riuniti di Ancona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppina","family":"Sanfilippo","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology and Neuroradiology, IRCCS Policlinico San Matteo, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Finocchi","sequence":"additional","affiliation":[{"name":"Department of Neurosciences, Policlinico Hospital San Martino, University of Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Diomedi","sequence":"additional","affiliation":[{"name":"Department of Systemic Medicine, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santino O","family":"Tomasi","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria"},{"name":"Laboratory for Microsurgical Neuroanatomy, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Palmisciano","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Trauma and Gamma-Knife Center, Cannizzaro Hospital, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe E","family":"Umana","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Trauma and Gamma-Knife Center, Cannizzaro Hospital, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Strigari","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2952-3812","authenticated-orcid":false,"given":"Christoph J","family":"Griessenauer","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Austria"},{"name":"Department of Neurosurgery, Geisinger Health System, Danville, PA, USA"},{"name":"Research Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3428-6660","authenticated-orcid":false,"given":"Francesca","family":"Pitocchi","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Garaci","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Floris","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,6,14]]},"reference":[{"key":"bibr1-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.023758"},{"key":"bibr2-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013316"},{"key":"bibr3-19714009221108673","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5640"},{"key":"bibr4-19714009221108673","doi-asserted-by":"publisher","DOI":"10.3171\/2021.4.FOCUS21111"},{"key":"bibr5-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(18)30236-6"},{"key":"bibr6-19714009221108673","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4965"},{"key":"bibr7-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.05.036"},{"key":"bibr8-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.118.021893"},{"key":"bibr9-19714009221108673","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00102"},{"key":"bibr10-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1111\/ene.13577"},{"key":"bibr11-19714009221108673","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"bibr12-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199811123392002"},{"key":"bibr13-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1111\/1754-9485.12170"},{"key":"bibr14-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804656"},{"key":"bibr15-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000158"},{"issue":"10","key":"bibr16-19714009221108673","first-page":"2602","volume":"26","author":"Abud DG","year":"2005","journal-title":"Am J Neuroradiol"},{"key":"bibr17-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1159\/000496292"},{"key":"bibr18-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31822b00cf"},{"key":"bibr19-19714009221108673","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A6768"},{"key":"bibr20-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.120.030038"},{"key":"bibr21-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1136\/neurintsurg-2017-013707"},{"key":"bibr22-19714009221108673","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A5404"},{"key":"bibr23-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurad.2019.01.089"},{"key":"bibr24-19714009221108673","doi-asserted-by":"publisher","DOI":"10.1177\/1747493020929948"}],"container-title":["The Neuroradiology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19714009221108673","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19714009221108673","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19714009221108673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:37:11Z","timestamp":1777588631000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19714009221108673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,14]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1177\/19714009221108673"],"URL":"https:\/\/doi.org\/10.1177\/19714009221108673","relation":{},"ISSN":["1971-4009","2385-1996"],"issn-type":[{"value":"1971-4009","type":"print"},{"value":"2385-1996","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,14]]}}}