{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T21:23:51Z","timestamp":1786569831839,"version":"build-2736575974"},"reference-count":12,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T00:00:00Z","timestamp":1692230400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neuroradiol J"],"published-print":{"date-parts":[[2024,2]]},"abstract":"\n Purpose<\/jats:title>\n Imaging changes in the pituitary volume during pregnancy remains scantly researched. This study set out to assess the differences in total, anterior, and posterior pituitary volume in pregnant women compared to nulliparous and post-partum women.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n A retrospective review was completed of women that had undergone MRI imaging of the brain. Patients were divided into three cohorts: pregnant, nulliparous, and post-partum (defined as being within 12\u00a0months of delivery). Anterior and posterior pituitary volumes were manually measured.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n 171 patients were included, of which 68 were pregnant, 52 were post-partum, and 51 were nulliparous. The average anterior (621.0 \u00b1 171.6\u00a0mm\n 3<\/jats:sup>\n ) and total (705.4 \u00b1 172.2\u00a0mm\n 3<\/jats:sup>\n ) pituitary volumes were significantly larger in pregnant patients than nulliparous women (522.6 \u00b1 159.8\u00a0mm\n 3<\/jats:sup>\n and 624.5 \u00b1 163.7\u00a0mm\n 3<\/jats:sup>\n , respectively) ( p = .002 and p = .01, respectively). The posterior pituitary volume was significantly smaller in pregnant women (84.4 \u00b1 32.9\u00a0mm\n 3<\/jats:sup>\n ) compared to both post-partum (101.2 \u00b1 42.0\u00a0mm\n 3<\/jats:sup>\n ) and nulliparous (102.0 \u00b1 46.1\u00a0mm\n 3<\/jats:sup>\n ) women ( p = .02 for both).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The anterior and total pituitary volumes are significantly larger during pregnancy persisting into the post-partum period. The posterior pituitary volume, conversely, decreases during pregnancy, and returns to its normal size in the post-partum period.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/19714009231196470","type":"journal-article","created":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T12:06:37Z","timestamp":1692273997000},"page":"39-42","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Pituitary volume changes in pregnancy and the post-partum period"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4038-5422","authenticated-orcid":false,"given":"John C","family":"Benson","sequence":"first","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6121-5166","authenticated-orcid":false,"given":"David F","family":"Malyuk","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1794-4502","authenticated-orcid":false,"given":"Ajay","family":"Madhavan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie B","family":"Guerin","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl N","family":"Krecke","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason T","family":"Little","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore J","family":"Passe","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David R","family":"DeLone","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward P","family":"Lindell","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence J","family":"Eckel","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mayo Clinic, Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,8,17]]},"reference":[{"key":"bibr1-19714009231196470","volume-title":"StatPearls","author":"Patel H","year":"2022"},{"key":"bibr2-19714009231196470","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1714"},{"key":"bibr3-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1097\/01.rmr.0000224682.91253.15"},{"key":"bibr4-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9343(88)80346-2"},{"key":"bibr5-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1016\/s0025-6196(12)60958-6"},{"key":"bibr6-19714009231196470","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.122608"},{"key":"bibr7-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1007\/BF02899695"},{"key":"bibr8-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2012.08.024"},{"key":"bibr9-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.07.198"},{"key":"bibr10-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1016\/s0025-6196(12)60946-x"},{"key":"bibr11-19714009231196470","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1968.28.2.0093"},{"key":"bibr12-19714009231196470","doi-asserted-by":"publisher","DOI":"10.1080\/02841859809172152"}],"container-title":["The Neuroradiology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19714009231196470","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/19714009231196470","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/19714009231196470","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:38:10Z","timestamp":1777588690000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/19714009231196470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,17]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1177\/19714009231196470"],"URL":"https:\/\/doi.org\/10.1177\/19714009231196470","relation":{},"ISSN":["1971-4009","2385-1996"],"issn-type":[{"value":"1971-4009","type":"print"},{"value":"2385-1996","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,17]]}}}