{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:36:03Z","timestamp":1792787763517,"version":"4.5.0"},"reference-count":33,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Shiraz University of Medical Sciences","id":[{"id":"https:\/\/ror.org\/01n3s4692","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neuroradiol J"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:p>\n                    Sexual dysfunction (SD), a prevalent yet underreported complication in multiple sclerosis (MS), significantly impacts quality of life. This cross-sectional study at Imam Reza Clinic, Shiraz University of Medical Sciences, evaluated SD prevalence in 80 relapsing-remitting MS (RRMS) patients (65 females and 15 males; mean age 38.7\u00a0years) compared to 80 demographically matched controls (61 females and 19 males; mean age 39.1\u00a0years). SD was assessed using the Female Sexual Function Index (FSFI) for females and the International Index of Erectile Function (IIEF) for males, alongside brain-focused MRI to examine morphological changes. Female RRMS patients had significantly lower FSFI scores (mean 21.80, SD 7.13) than controls (mean 27.86, SD 4.83;\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; .001). FSFI scores negatively correlated with cerebrospinal fluid volume (r = \u22120.297,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = .016), disease duration (r = \u22120.319,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = .010), fatigue (r = \u22120.412,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = .001), and depression (r = \u22120.387,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = .002). Male RRMS patients showed lower IIEF scores (mean 64.40, SD 8.77) compared to controls (mean 73.21, SD 2.84;\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = .0012), with positive correlations between IIEF scores and insular cortex volume (r = 0.576,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = .025), cerebellar grey matter volume (r = 0.727,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    = .002), and total grey matter volume (r = 0.846,\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; .001). Multivariate regression identified MRI measurements, disease duration, and fatigue as independent SD predictors (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    &lt; .05). The high SD prevalence in RRMS, with distinct sex-specific neuroimaging correlates, highlights the need for routine SD screening and tailored interventions in MS care to improve patient outcomes.\n                  <\/jats:p>","DOI":"10.1177\/19714009261423698","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T21:16:37Z","timestamp":1771017397000},"page":"658-663","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of sexual dysfunction in relapsing-remitting multiple sclerosis and its association with brain and cervical cord MRI findings"],"prefix":"10.1177","volume":"39","author":[{"given":"Behnam","family":"Dousty","sequence":"first","affiliation":[{"name":"Shiraz University of Medical Sciences"},{"name":"Shiraz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeideh","family":"Karimi","sequence":"additional","affiliation":[{"name":"Shiraz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Torabi Jahromi","sequence":"additional","affiliation":[{"name":"Shiraz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Forough","family":"Alizadeh","sequence":"additional","affiliation":[{"name":"Shiraz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4815-0345","authenticated-orcid":false,"given":"Banafsheh","family":"Zeinali-Rafsanjani","sequence":"additional","affiliation":[{"name":"Shiraz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8134-7182","authenticated-orcid":false,"given":"Parisa","family":"Pishdad","sequence":"additional","affiliation":[{"name":"Shiraz University of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,13]]},"reference":[{"key":"e_1_3_9_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458520970841"},{"key":"e_1_3_9_3_2","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2017.4410"},{"key":"e_1_3_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2021.103336"},{"key":"e_1_3_9_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.26858"},{"key":"e_1_3_9_6_2","article-title":"Investigating depression and MRI associations in Middle Eastern relapsing-remitting multiple sclerosis","author":"Pishdad P","year":"2025","unstructured":"Pishdad P, Zeinali-Rafsanjani B, Poursadeghfard M, et al. Investigating depression and MRI associations in Middle Eastern relapsing-remitting multiple sclerosis. J Biomed Phy Eng 2025.","journal-title":"J Biomed Phy Eng"},{"key":"e_1_3_9_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2011.110"},{"issue":"2","key":"e_1_3_9_8_2","first-page":"274","article-title":"Sexual dysfunction in Neurological disorders: do we see just the tip of the iceberg?","volume":"89","author":"Calabr\u00f2 RS","year":"2018","unstructured":"Calabr\u00f2 RS. Sexual dysfunction in Neurological disorders: do we see just the tip of the iceberg? 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