{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:01:16Z","timestamp":1780732876812,"version":"3.54.1"},"reference-count":23,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Neuroradiol J"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Intracranial arterial stenosis is a major cause of ischemic stroke in Asian populations. High-resolution magnetic resonance imaging (HR-MRI) of the vessel wall is an emerging tool that offers valuable insights.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective study of adult patients (\u226518 years) with acute ischemic stroke and M1 MCA stenosis who underwent HR-MRI at the University Medical Center Ho Chi Minh City between January 2019 and May 2025.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixty-two patients were included (mean age, 56 \u00b1 13 years; male-to-female ratio, 2:1). The average stenosis degree was 66.3 \u00b1 17.5, with severe stenosis in 38.7% of patients. The predominant pattern was eccentric stenosis (80.6%), more frequently observed in older patients. The mean remodeling index was 0.87 \u00b1 0.21, and most cases showed negative remodeling. The majority of lesions at the stenotic site exhibited post-contrast enhancement, most commonly grade 2 enhancement (43.6%). The most frequent cause of stenosis was atherosclerosis (43 cases), followed by dissection (2 cases), Moyamoya disease (1 case), and indeterminate etiology (16 cases). Among infarct-associated atherosclerotic lesions, plaques with intraplaque hemorrhage (58.1%), irregular plaque surface (86.1%), and strong (grade 3) enhancement (46.5%) were observed more frequently than in the small non\u2013infarct-associated incidental group; however, this exploratory comparison was limited by the very small size of the comparator group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>HR-MRI of the MCA vessel wall provides detailed information on stenotic lesion characteristics, aiding in the identification of the underlying etiology. These findings highlight the potential role of HR-MRI in stroke diagnosis and risk stratification in Vietnamese patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/19714009261450384","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:15:47Z","timestamp":1780568147000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Vessel wall characteristics of the middle cerebral artery on high-resolution magnetic resonance imaging in patients with acute ischemic stroke"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-4376-1443","authenticated-orcid":false,"given":"Thi Bich Nga","family":"Le","sequence":"first","affiliation":[{"name":"Department of Imaging, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thi Thuy Linh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Imaging, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0728-6139","authenticated-orcid":false,"given":"Duy Khoa","family":"Dao","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medical Center HCMC, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1183-388X","authenticated-orcid":false,"given":"Vinh Khang","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Medical Center HCMC, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phuong Truc","family":"Vo","sequence":"additional","affiliation":[{"name":"Department of Imaging, University Medical Center HCMC, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Van Phuoc","family":"Le","sequence":"additional","affiliation":[{"name":"Department of Imaging, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1159\/000438779"},{"key":"e_1_3_4_3_2","article-title":"Intracranial arterial stenosis on 3.0 Tesla Magnetic Resonance Imaging at Bach Mai Hospital","volume":"519","author":"Do HH","year":"2022","unstructured":"Do HH, Pham MT, Tran AT, et al. Intracranial arterial stenosis on 3.0 Tesla Magnetic Resonance Imaging at Bach Mai Hospital. Vietnam Medical Journal 2022; 519. https:\/\/doi.org\/10.51298\/vmj.v519i1.3549","journal-title":"Vietnam Medical Journal"},{"key":"e_1_3_4_4_2","first-page":"62","article-title":"Vessel wall characteristics on High-Resolution MRI of Ischemic Stroke associated with Intracranial Stenosis","volume":"25","author":"Pham TNQ","year":"2021","unstructured":"Pham TNQ, Phan CC, Doan TD, et al. Vessel wall characteristics on High-Resolution MRI of Ischemic Stroke associated with Intracranial Stenosis. 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