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We describe how to safely treat a retroperitoneal target to a prescription dose over 70\u2009Gy (relative biological effectiveness) with spot-scanning proton beam therapy and also report a dosimetric comparison of spot-scanning proton beam therapy versus intensity-modulated radiation therapy. This case not only highlights a rare diagnosis of an extravertebral retroperitoneal chordoma but it also draws attention to the dosimetric advantages of proton beam therapy and illustrates a promising radiotherapeutic option for retroperitoneal targets.<\/jats:p>","DOI":"10.1177\/2036361319878518","type":"journal-article","created":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T03:59:16Z","timestamp":1569211156000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Dosimetric advantages of proton beam therapy compared to intensity-modulated radiation therapy for retroperitoneal chordoma"],"prefix":"10.1177","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4059-650X","authenticated-orcid":false,"given":"Nathan Y","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sujay A","family":"Vora","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,9,23]]},"reference":[{"key":"bibr1-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-015-9311-x"},{"key":"bibr2-2036361319878518","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2001.10.3.13"},{"key":"bibr3-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.jor.2018.04.001"},{"issue":"13","key":"bibr4-2036361319878518","first-page":"923","volume":"152","author":"Enehjelm SD","year":"1990","journal-title":"Ugeskr Laeger"},{"issue":"2","key":"bibr5-2036361319878518","first-page":"157","volume":"33","author":"Mihaila G","year":"1995","journal-title":"Rom J Neurol Psychiatry"},{"key":"bibr6-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2017.06.038"},{"key":"bibr7-2036361319878518","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1999.91.3.0432"},{"key":"bibr8-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-8140(96)91805-8"},{"key":"bibr9-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23617"},{"key":"bibr10-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2015.05.024"},{"key":"bibr11-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(95)02014-3"},{"key":"bibr12-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000000611"},{"key":"bibr13-2036361319878518","doi-asserted-by":"publisher","DOI":"10.3171\/2009.9.JNS08596"},{"key":"bibr14-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2016.05.035"},{"key":"bibr15-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1097\/PPO.0000000000000084"},{"key":"bibr16-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2017.12.017"},{"key":"bibr17-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2012.02.001"},{"key":"bibr18-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2007.12.009"},{"issue":"157","key":"bibr19-2036361319878518","first-page":"145","volume":"40","author":"Thompson PL","year":"1971","journal-title":"Q J Med"},{"key":"bibr20-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(86)90284-1"},{"key":"bibr21-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.02.089"},{"key":"bibr22-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(91)90171-Y"},{"key":"bibr23-2036361319878518","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2013.09.053"}],"container-title":["Rare Tumors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2036361319878518","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/2036361319878518","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/2036361319878518","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:10:17Z","timestamp":1777590617000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/2036361319878518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":23,"alternative-id":["10.1177\/2036361319878518"],"URL":"https:\/\/doi.org\/10.1177\/2036361319878518","relation":{},"ISSN":["2036-3613","2036-3613"],"issn-type":[{"value":"2036-3613","type":"print"},{"value":"2036-3613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"article-number":"2036361319878518"}}