{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:01:05Z","timestamp":1777878065921,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016168","name":"king hussein cancer center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016168","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Rare Tumors"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Germ cell tumors are a heterogeneous group of tumors that can present primarily as gonadal tumors in either a localized or metastatic pattern. Rarely these tumors can initially present at extra-gonadal locations, including the gastrointestinal tract. We report two young male patients who presented with nonspecific gastrointestinal symptoms caused by a mass lesion involving the duodenum. Pathologically, both were confirmed to be germ cell tumors; an unfamiliar initial presentation of germ cell tumors. In both cases, evidence of pre-existing gonadal tumor in the form of a testicular mass and a burned-out tumor with microlithiasis, in the first and second cases, respectively was detected following the confirmed diagnosis of extra-gonadal germ cell tumor. Each patient\u2019s clinical course and outcome emphasizes the importance of a high index of suspicion, timely diagnosis, and appropriate management.<\/jats:p>","DOI":"10.1177\/20363613211029487","type":"journal-article","created":{"date-parts":[[2021,6,30]],"date-time":"2021-06-30T12:15:37Z","timestamp":1625055337000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Extragonadal germ cell tumor, a report of two cases presenting in the gastrointestinal tract"],"prefix":"10.1177","volume":"13","author":[{"given":"Mousa","family":"Elkhaldi","sequence":"first","affiliation":[{"name":"Department of Radiology, King Hussein Cancer Center, Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8417-9911","authenticated-orcid":false,"given":"Ahamd Moayad","family":"Naser","sequence":"additional","affiliation":[{"name":"Office of Scientific Affairs and Research, King Hussein Cancer Center, Amman Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yazan","family":"AlHalaseh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, King Hussein Cancer Center, Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maysa","family":"Al-Hussaini","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,6,30]]},"reference":[{"key":"bibr1-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1016\/j.path.2019.01.005"},{"key":"bibr2-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.07.062"},{"key":"bibr3-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2003.tb01408.x"},{"key":"bibr4-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdf669"},{"key":"bibr5-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.2011.01245.x"},{"key":"bibr6-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.08.020"},{"key":"bibr7-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(04)01385-3"},{"key":"bibr8-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e32835f085d"},{"key":"bibr9-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65201-9"},{"key":"bibr10-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-2042.1999.06314.x"},{"key":"bibr11-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1159\/000020368"},{"key":"bibr12-20363613211029487","doi-asserted-by":"publisher","DOI":"10.4318\/tjg.2011.0291"},{"key":"bibr13-20363613211029487","first-page":"297","volume":"38","author":"Palacios Soto P","year":"2018","journal-title":"Rev Gastroenterol Peru"},{"key":"bibr14-20363613211029487","first-page":"134","volume":"3","author":"Kucukoner M","year":"2012","journal-title":"World J Oncol"},{"key":"bibr15-20363613211029487","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.20774.1"},{"key":"bibr16-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-010-0183-8"},{"key":"bibr17-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1207\/S15328015TLM1002_2"},{"key":"bibr18-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.130135mb"},{"key":"bibr19-20363613211029487","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.07.062"}],"container-title":["Rare Tumors"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20363613211029487","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/20363613211029487","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/20363613211029487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T23:10:51Z","timestamp":1777590651000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/20363613211029487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":19,"alternative-id":["10.1177\/20363613211029487"],"URL":"https:\/\/doi.org\/10.1177\/20363613211029487","relation":{},"ISSN":["2036-3613","2036-3613"],"issn-type":[{"value":"2036-3613","type":"print"},{"value":"2036-3613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"article-number":"20363613211029487"}}